Neuregulin 3 产品
(Neuregulin 3 (NRG3))
Categories
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009].
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Featured Neuregulin 3 Categories
Neuregulin 3 抗体
High quality antibodies with extensive validation data.
Neuregulin 3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Neuregulin 3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Neuregulin 3 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p)
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- (4)
Cat. No.
ABIN3181485
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN7187474
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7191717
Quantity
100 μL
Datasheet
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Recommended Neuregulin 3 ELISA试剂盒
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Reactivity
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Analytical Method
Quantitative Sandwich ELISA
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Cat. No.
ABIN6968854
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96 tests
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Reactivity
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Quantitative Sandwich ELISA
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- (1)
Cat. No.
ABIN1571584
Quantity
96 tests
Datasheet
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Reactivity
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Quantitative Sandwich ELISA
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ABIN6951189
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96 tests
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Recommended Neuregulin 3 蛋白
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Tobacco (Nicotiana tabacum)
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- (1)
Cat. No.
ABIN3114012
Quantity
1 mg
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Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
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Cat. No.
ABIN3131461
Quantity
1 mg
Datasheet
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Reactivity
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Insect Cells
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ABIN3084744
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Latest Publications for our Neuregulin 3 Products
: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).: "Levels of neuregulin 1 and 3 proteins in Brodmann's area 46 from subjects with schizophrenia and bipolar disorder." in: Neuroscience letters, Vol. 466, Issue 1, pp. 27-9, (2009) (PubMed).
: "Dynamic expression of Erbb pathway members during early mammary gland morphogenesis." in: The Journal of investigative dermatology, Vol. 128, Issue 4, pp. 1009-21, (2008) (PubMed).
: "Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification." in: Genes & development, Vol. 19, Issue 17, pp. 2078-90, (2005) (PubMed).
: "Human NRG3 gene Map position 10q22-q23." in: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, Vol. 8, Issue 6, pp. 560, (2001) (PubMed).
: "NRG-3 in human breast cancers: activation of multiple erbB family proteins." in: International journal of oncology, Vol. 13, Issue 5, pp. 1061-7, (1998) (PubMed).
: "Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 18, pp. 9562-7, (1997) (PubMed).
Synonyms and alternative names related to Neuregulin 3
neuregulin 3 (NRG3), neuregulin 3 (nrg3), pro-neuregulin-3, membrane-bound isoform (LOC100478170), neuregulin 3 (Nrg3), HRG3, NRG3, pro-NRG3, RGD1559678, skaProtein level used designations for Neuregulin 3
- neuregulin 3
- pro-neuregulin-3, membrane-bound isoform-like
- neuregulin 3 variant 1
- neuregulin 3 variant 10
- neuregulin 3 variant 11
- neuregulin 3 variant 12
- neuregulin 3 variant 13
- neuregulin 3 variant 14
- neuregulin 3 variant 3
- neuregulin 3 variant 4
- neuregulin 3 variant 5
- neuregulin 3 variant 6
- neuregulin 3 variant 7
- neuregulin 3 variant 8
- neuregulin 3 variant 9
- neuregulin-3-like polypeptide
- pro-neuregulin-3, membrane-bound isoform
- pro-NRG3
- scaramanga
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