电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

neonatal Fc Receptor 蛋白

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Active filters:

  • 抗原: FcRn
  • Protein
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7866698
FcRn Protein (AA 24-297) (His tag) FcRn · Protein 人 HEK-293 Cells
  • 50 μg
发货至: 中国
ABIN7950699
FcRn Protein (His tag) FcRn · Protein 小鼠 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
  • 1 mg
  • 50 μg
发货至: 中国
ABIN7943515
FcRn Protein (His tag) FcRn · Protein 人 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
  • 1 mg
  • 50 μg
发货至: 中国
ABIN2720991
FcRn Protein (Transcript Variant 2) FcRn · Protein 人 HEK-293 Cells
  • AbP (Antibody Production: 所列应用)
  • STD (Standard: 所列应用)
  • 10 μg
发货至: 中国
Protein
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7866698
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
宿主
小鼠
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
产品编号 ABIN7950699
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
宿主
人
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
产品编号 ABIN7943515
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • AbP (Antibody Production: 所列应用)
  • STD (Standard: 所列应用)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by SDS-PAGE and Coomassie blue staining
产品编号 ABIN2720991

Latest Publications for our neonatal Fc Receptor 蛋白

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliases for neonatal Fc Receptor 蛋白

Fc fragment of IgG receptor and transporter (FCGRT) 蛋白
Fc fragment of IgG receptor and transporter (Fcgrt) 蛋白
Fc receptor, IgG, alpha chain transporter (Fcgrt) 蛋白
alpha-chain 蛋白
FCRN 蛋白
FcRn 蛋白
You are here: