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neonatal Fc Receptor 蛋白

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Active filters:

  • 抗原: FcRn
  • Protein
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7274677
FcRn Protein (AA 22-297) (His tag) FcRn · Protein 小鼠 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7274675
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Cynomolgus, 猕猴 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • ELISA (ELISA: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7274676
FcRn Protein (AA 24-297) (His tag) FcRn · Protein 人 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • ELISA (ELISA: 有验证图片)
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7536880
FcRn Protein (AA 24-297) (His-Avi Tag,Biotin) FcRn · Protein 人 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • 250 μg
  • 5 x 250 μg
发货至: 中国
ABIN7536879
FcRn Protein (AA 24-297) (His-Avi Tag) FcRn · Protein 人 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • 1 mg
  • 5 x 1 mg
发货至: 中国
ABIN1353903
FcRn Protein (AA 51-160) (GST tag) FcRn · Protein 人 小麦胚
  • AP (Affinity Purification: 所列应用)
  • AA (Antibody Array: 所列应用)
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
  • 10 μg
  • 25 μg
发货至: 中国
ABIN5854760
FcRn Protein (AA 22-297) (His tag) FcRn · Protein 小鼠 Baculovirus infected Insect Cells
  • SDS (SDS-PAGE: 有验证图片)
  • 50 μg
  • 10 μg
  • 250 μg
发货至: 中国
ABIN2870741
FcRn Protein (AA 22-297) (His tag,Strep Tag) FcRn · Protein 小鼠 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • ELISA (ELISA: 有验证图片)
  • 50 μg
  • 1 mg
  • 100 μg
发货至: 中国
ABIN2870550
FcRn Protein (AA 24-297) (His tag,Strep Tag,AVI tag,Biotin) FcRn · Protein 人 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
  • 200 μg
  • 25 μg
发货至: 中国
ABIN2181081
FcRn Protein (AA 24-297) (His tag,Strep Tag) FcRn · Protein Cynomolgus, 猕猴 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
  • 50 μg
  • 1 mg
  • 100 μg
发货至: 中国
ABIN2181085
FcRn Protein (AA 24-297) (His tag,Strep Tag) FcRn · Protein 人 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
  • 50 μg
  • 1 mg
  • 100 μg
发货至: 中国
ABIN7580616
FcRn Protein (His tag) FcRn · Protein 小鼠 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7678672
FcRn Protein (AA 22-301) (His tag) FcRn · Protein 小鼠 Mammalian Cells
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
  • AcA (Activity Assay: 所列应用)
  • 100 μg
  • 50 μg
发货至: 中国
ABIN2115488
FcRn Protein (AA 21-119, AA 24-290) (His tag) FcRn · Protein 人 人细胞
  • 50 μg
  • 1 mg
  • 10 μg
  • 500 μg
发货至: 中国
ABIN7889635
FcRn Protein (AA 21-119, AA 22-297) (His tag) FcRn · Protein 小鼠 HEK-293 Cells
  • 10 μg
发货至: 中国
ABIN7889636
FcRn Protein (AA 21-119, AA 24-297, Heterodimer) (His tag) FcRn · Protein 人 人细胞
  • 10 μg
发货至: 中国
ABIN7889637
FcRn Protein (AA 21-119, AA 24-297) (His-Avi Tag,Biotin) FcRn · Protein 人 人细胞
  • 100 μg
发货至: 中国
ABIN7534672
FcRn 蛋白 FcRn · Protein 人 HEK-293 Cells
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 50 μg
  • 500 μg
发货至: 中国
ABIN7583297
FcRn Protein (AA 23-298) (His tag) FcRn · Protein 大鼠 HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
ABIN7504325
FcRn Protein (AA 22-297) (Biotin,His-Avi Tag) FcRn · Protein 小鼠 HEK-293 Cells
  • 100 μg
  • 500 μg
发货至: 中国
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
宿主
小鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7274677
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • ELISA (ELISA: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
宿主
Cynomolgus, 猕猴
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7274675
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • ELISA (ELISA: 有验证图片)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7274676
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % by SEC-HPLC
产品编号 ABIN7536880
250 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: 有验证图片)
  • SPR (Surface Plasmon Resonance: 有验证图片)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % by SEC-HPLC
产品编号 ABIN7536879
1 mg (More quantities available)
发货至: 中国
获取报价
Protein
  • AP (Affinity Purification: 所列应用)
  • AA (Antibody Array: 所列应用)
  • ELISA (ELISA: 所列应用)
  • WB (Western Blotting: 所列应用)
宿主
人
宿主
小麦胚
蛋白类型
Recombinant
产品编号 ABIN1353903
Protein
  • SDS (SDS-PAGE: 有验证图片)
宿主
小鼠
宿主
Baculovirus infected Insect Cells
蛋白类型
Recombinant
纯度
> 85 %
产品编号 ABIN5854760
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • ELISA (ELISA: 有验证图片)
宿主
小鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
产品编号 ABIN2870741
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2870550
200 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
宿主
Cynomolgus, 猕猴
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2181081
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2181085
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
宿主
小鼠
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
产品编号 ABIN7580616
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • ELISA (ELISA: 所列应用)
  • AcA (Activity Assay: 所列应用)
宿主
小鼠
宿主
Mammalian Cells
蛋白类型
Recombinant
纯度
>90 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN7678672
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
人
宿主
人细胞
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN2115488
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
小鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
产品编号 ABIN7889635
Protein
宿主
人
宿主
人细胞
蛋白类型
Recombinant
产品编号 ABIN7889636
Protein
宿主
人
宿主
人细胞
蛋白类型
Recombinant
产品编号 ABIN7889637
Protein
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 97 % by SDS-PAGE.
生物活性
Active
产品编号 ABIN7534672
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
大鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7583297
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
宿主
小鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
生物活性
Active
产品编号 ABIN7504325
100 μg (More quantities available)
发货至: 中国
获取报价

Latest Publications for our neonatal Fc Receptor 蛋白

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliases for neonatal Fc Receptor 蛋白

Fc fragment of IgG receptor and transporter (FCGRT) 蛋白
Fc fragment of IgG receptor and transporter (Fcgrt) 蛋白
Fc receptor, IgG, alpha chain transporter (Fcgrt) 蛋白
alpha-chain 蛋白
FCRN 蛋白
FcRn 蛋白
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