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neonatal Fc Receptor 蛋白

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Active filters:

  • 抗原: FcRn
  • Protein
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN7576943
FcRn Protein (His tag) FcRn · Protein 人 Mammalian Cells
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • 100 μg
发货至: 中国
ABIN7853548
FcRn Protein (AA 24-297) (His tag) FcRn · Protein 人 HEK-293 Cells
  • AM (Affinity Measurement: 所列应用)
  • ADA (Antibody Drug Assay: 所列应用)
  • IA (Immunoassay: 所列应用)
  • ScA (Screening Assay: 所列应用)
  • 100 μg
  • 10 μg
  • 50 μg
发货至: 中国
ABIN8057043
FcRn Protein (AA 21-119, AA 24-297, Heterodimer) (His-Avi Tag,Biotin) FcRn · Protein 人 HEK-293 Cells
  • BLI (Bio-Layer Interferometry: 所列应用)
  • 100 μg
发货至: 中国
ABIN7403297
FcRn Protein (AA 24-365) (His tag) FcRn · Protein 人 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • PC (Positive Control: 所列应用)
  • 100 μg
  • 1 mg
  • 10 μg
  • 50 μg
  • 200 μg
  • 500 μg
发货至: 中国
ABIN2870582
FcRn Protein (AA 23-298) (His tag,Strep Tag,AVI tag,Biotin) FcRn · Protein 大鼠 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
  • 200 μg
  • 25 μg
发货至: 中国
ABIN2181083
FcRn Protein (AA 23-298) (His tag,Strep Tag) FcRn · Protein 大鼠 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • 50 μg
  • 1 mg
  • 100 μg
发货至: 中国
ABIN2870526
FcRn Protein (AA 24-297) (His tag,AVI tag,Strep Tag,Biotin) FcRn · Protein Cynomolgus, 猕猴 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • 200 μg
  • 25 μg
发货至: 中国
ABIN2444126
FcRn Protein (AA 24-297) (His tag,Strep Tag,Biotin) FcRn · Protein 人 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
  • 200 μg
  • 25 μg
发货至: 中国
ABIN2870570
FcRn Protein (AA 22-297) (His tag,Strep Tag,AVI tag,Biotin) FcRn · Protein 小鼠 HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
  • 200 μg
  • 25 μg
发货至: 中国
ABIN2720989
FcRn Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) FcRn · Protein 人 HEK-293 Cells
  • WB (Western Blotting: 有验证图片)
  • AbP (Antibody Production: 所列应用)
  • STD (Standard: 所列应用)
  • 20 μg
发货至: 中国
ABIN1643585
FcRn Protein (AA 24-297) (His tag) FcRn · Protein Cynomolgus 酵母菌
  • SDS (SDS-PAGE: 有验证图片)
  • ELISA (ELISA: 所列应用)
  • 1 mg
发货至: 中国
ABIN4949195
FcRn Protein (AA 16-289) (His tag,Strep Tag) FcRn · Protein Pig HEK-293 Cells
  • SDS (SDS-PAGE: 有验证图片)
  • Func (Functional Studies: 所列应用)
  • 50 μg
  • 1 mg
  • 100 μg
发货至: 中国
ABIN5709509
FcRn Protein (AA 24-297, Extracellular) (GST tag) FcRn · Protein 人 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 有验证图片)
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 200 μg
  • 500 μg
发货至: 中国
ABIN5711682
FcRn Protein (AA 24-297, Extracellular) (His-SUMO Tag) FcRn · Protein Macaca (Macaque) 大肠杆菌(E. Coli)
  • SDS (SDS-PAGE: 有验证图片)
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 200 μg
  • 500 μg
发货至: 中国
ABIN5713450
FcRn Protein (AA 24-297, Extracellular) (His tag) FcRn · Protein 人 酵母菌
  • SDS (SDS-PAGE: 有验证图片)
  • 100 μg
  • 1 mg
  • 10 μg
  • 20 μg
  • 200 μg
  • 500 μg
发货至: 中国
ABIN2720990
FcRn Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) FcRn · Protein 人 HEK-293 Cells
  • WB (Western Blotting: 有验证图片)
  • AbP (Antibody Production: 所列应用)
  • STD (Standard: 所列应用)
  • 20 μg
发货至: 中国
ABIN1473931
FcRn Protein (AA 23-298) (His tag) FcRn · Protein 大鼠 酵母菌
  • ELISA (ELISA: 所列应用)
  • 1 mg
发货至: 中国
ABIN7819986
FcRn Protein (AA 25-292) (His tag) FcRn · Protein 小鼠 Bacteria
  • 100 μg
发货至: 中国
ABIN7816356
FcRn Protein (AA 24-365) (His tag) FcRn · Protein 人 Bacteria
  • 100 μg
发货至: 中国
ABIN7866978
FcRn Protein (AA 24-297) (His tag) FcRn · Protein 人 HEK-293 Cells
  • 50 μg
发货至: 中国
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
宿主
人
宿主
Mammalian Cells
蛋白类型
Recombinant
产品编号 ABIN7576943
Protein
  • AM (Affinity Measurement: 所列应用)
  • ADA (Antibody Drug Assay: 所列应用)
  • IA (Immunoassay: 所列应用)
  • ScA (Screening Assay: 所列应用)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7853548
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • BLI (Bio-Layer Interferometry: 所列应用)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 95 % as determined by reducing SDS-PAGE.
生物活性
Active
产品编号 ABIN8057043
Protein
  • SDS (SDS-PAGE: 所列应用)
  • WB (Western Blotting: 所列应用)
  • Imm (Immunogen: 所列应用)
  • PC (Positive Control: 所列应用)
宿主
人
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
纯度
> 90 %
产品编号 ABIN7403297
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
宿主
大鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2870582
200 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
宿主
大鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
产品编号 ABIN2181083
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
宿主
Cynomolgus, 猕猴
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>90 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2870526
200 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2444126
200 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Bind (Binding Studies: 有验证图片)
宿主
小鼠
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
生物活性
Active
产品编号 ABIN2870570
200 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • WB (Western Blotting: 有验证图片)
  • AbP (Antibody Production: 所列应用)
  • STD (Standard: 所列应用)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 80 % as determined by SDS-PAGE and Coomassie blue staining
产品编号 ABIN2720989
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • ELISA (ELISA: 所列应用)
宿主
Cynomolgus
宿主
酵母菌
蛋白类型
Recombinant
纯度
> 90 %
产品编号 ABIN1643585
Protein
  • SDS (SDS-PAGE: 有验证图片)
  • Func (Functional Studies: 所列应用)
宿主
Pig
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
>95 % as determined by SDS-PAGE.
产品编号 ABIN4949195
50 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
宿主
人
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
纯度
Greater than 90 % as determined by SDS-PAGE.
产品编号 ABIN5709509
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
宿主
Macaca (Macaque)
宿主
大肠杆菌(E. Coli)
蛋白类型
Recombinant
纯度
Greater than 90 % as determined by SDS-PAGE.
产品编号 ABIN5711682
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • SDS (SDS-PAGE: 有验证图片)
宿主
人
宿主
酵母菌
蛋白类型
Recombinant
纯度
Greater than 90 % as determined by SDS-PAGE.
产品编号 ABIN5713450
100 μg (More quantities available)
发货至: 中国
获取报价
Protein
  • WB (Western Blotting: 有验证图片)
  • AbP (Antibody Production: 所列应用)
  • STD (Standard: 所列应用)
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
> 80 % as determined by SDS-PAGE and Coomassie blue staining
产品编号 ABIN2720990
Protein
  • ELISA (ELISA: 所列应用)
宿主
大鼠
宿主
酵母菌
蛋白类型
Recombinant
纯度
> 90 %
产品编号 ABIN1473931
Protein
宿主
小鼠
宿主
Bacteria
蛋白类型
Recombinant
产品编号 ABIN7819986
Protein
宿主
人
宿主
Bacteria
蛋白类型
Recombinant
产品编号 ABIN7816356
Protein
宿主
人
宿主
HEK-293 Cells
蛋白类型
Recombinant
纯度
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7866978

Latest Publications for our neonatal Fc Receptor 蛋白

Spencer, Goldberg, Pandey, Ordonez, Dufloo, Barnette, Sutton, Henderson, Agnor, Gao, Bruel, Schwartz, Haigwood, Ackerman, Hessell: "Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis." in: Nature communications, Vol. 13, Issue 1, pp. 662, (2022) (PubMed).

Kisalu, Pereira, Ernste, Flores-Garcia, Idris, Asokan, Dillon, MacDonald, Shi, Chen, Pegu, Schön, Zavala, Balazs, Francica, Seder: "Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Asokan, Dias, Liu, Maximova, Ernste, Pegu, McKee, Shi, Chen, Almasri, Promsote, Ambrozak, Gama, Hu, Douek, Todd, Lifson, Fourati, Sekaly, Crowley, Ackerman, Ko, Kilam, Boritz, Liao, Best, Perelson et al.: "Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18754-18763, (2020) (PubMed).

Zhao, Gao, Yu, Li, Zhang, Zhang, Lu, Gao, Guo: "Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses." in: Molecular and cellular endocrinology, Vol. 477, pp. 103-111, (2019) (PubMed).

Simonov, Ivanov, Smolov, Abbasova, Piskunov, Poteryaev: "Control of therapeutic IgG antibodies galactosylation during cultivation process and its impact on IgG1/FcγR interaction and ADCC activity." in: Biologicals : journal of the International Association of Biological Standardization, Vol. 58, pp. 16-21, (2019) (PubMed).

Yang, Kim, Seong, Tae, Kwon: "Comparative studies of the serum half-life extension of a protein via site-specific conjugation to a species-matched or -mismatched albumin." in: Biomaterials science, Vol. 6, Issue 8, pp. 2092-2100, (2018) (PubMed).

Kenniston, Taylor, Conley, Cosic, Kopacz, Lindberg, Comeau, Atkins, Bullen, TenHoor, Adelman, Sexton, Edwards, Nixon: "Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody." in: The Journal of biological chemistry, Vol. 292, Issue 42, pp. 17449-17460, (2017) (PubMed).

Zhou, Wang, Tong, Okamoto, Shen, Zaro: "Single chain Fc-dimer-human growth hormone fusion protein for improved drug delivery." in: Biomaterials, Vol. 117, pp. 24-31, (2017) (PubMed).

Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

Deissler, Lang, Lang: "Internalization of bevacizumab by retinal endothelial cells and its intracellular fate: Evidence for an involvement of the neonatal Fc receptor." in: Experimental eye research, Vol. 143, pp. 49-59, (2015) (PubMed).

Aliases for neonatal Fc Receptor 蛋白

Fc fragment of IgG receptor and transporter (FCGRT) 蛋白
Fc fragment of IgG receptor and transporter (Fcgrt) 蛋白
Fc receptor, IgG, alpha chain transporter (Fcgrt) 蛋白
alpha-chain 蛋白
FCRN 蛋白
FcRn 蛋白
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