The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009].
Kim, Kim, An, Kang, Park, Hwang, Seo, Jang, Ha, Lee: "NELL2 Function in Axon Development of Hippocampal Neurons." in: Molecules and cells, Vol. 43, Issue 6, pp. 581-589, (2020) (PubMed).
Aliases for NELL2 蛋白
neural EGFL like 2 L homeolog (nell2.L) 蛋白 NEL-like 2 (Nell2) 蛋白 neural EGFL like 2 (NELL2) 蛋白 neural EGFL like 2 (Nell2) 蛋白 neural EGFL like 2a (nell2a) 蛋白 A330108N19Rik 蛋白 mel91 蛋白 nel 蛋白 nell2 蛋白 NRP2 蛋白 R75516 蛋白 wu:fj43h11 蛋白 zgc:158375 蛋白