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PKD1 抗体

(Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on chromosome 16p, have been described. [provided by RefSeq, Oct 2008].
PKD1 抗体  (AA 131-230) PKD1 抗体  (AA 131-230) PKD1 抗体 (AA 131-230) (ABIN678083)

PKD1 适用: 人, 小鼠 ELISA, WB, IHC (p), FACS, IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

PKD1 抗体  (AA 615-753) PKD1 抗体  (AA 615-753) PKD1 抗体 (AA 615-753) (ABIN7163832)

PKD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PKD1 抗体 PKD1 抗体 PKD1 抗体 (ABIN7238054)

PKD1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

PKD1 抗体 by Grade

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PKD1 抗体 by 适用

Find PKD1 抗体 for a variety of species such as anti-Human PKD1, anti-Mouse PKD1, anti-Rat PKD1. The species listed below are among those available. Click on a link to go to the corresponding products.

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PKD1 抗体 by 抗原表位

Find PKD1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PKD1 抗体 by 克隆形成能力

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PKD1 抗体 by 标记

Find PKD1 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PKD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC (p), FACS, IF (cc), IF (p), IHC (fro), ICC
Validations
  • (4)
  • (1)
Cat. No. ABIN678083
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7163832
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238054
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (1)
Cat. No. ABIN3186481
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (1)
Cat. No. ABIN3186482
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB, IF
Validations
  • (1)
Cat. No. ABIN3186483
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC, WB
Validations
  • (1)
Cat. No. ABIN3182603
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN3182229
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse, Pig, Rat
Application ELISA
Validations
  • (1)
Cat. No. ABIN768558
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC (p), IHC (fro)
Validations
Cat. No. ABIN678085
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN911683
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN911680
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN911684
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN2805478
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN911682
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PKD1 抗体

Ren, Xia, Yang, Zhu, Zhang, Chen, Zhao, Sun, Zhao: "Down-regulation of polycystin in lymphatic malformations: possible role in the proliferation of lymphatic endothelial cells." in: Human pathology, Vol. 65, pp. 231-238, (2017) (PubMed).

Kito, Saigo, Takeuchi: "Novel Transgenic Mouse Model of Polycystic Kidney Disease." in: The American journal of pathology, Vol. 187, Issue 9, pp. 1916-1922, (2017) (PubMed).

Ohata, Herranz-Pérez, Nakatani, Boletta, García-Verdugo, Álvarez-Buylla: "Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 31, pp. 11153-68, (2015) (PubMed).

Chiou, Sang, Cheng, Ho, Wang, Pan: "Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors." in: Carcinogenesis, Vol. 34, Issue 6, pp. 1315-22, (2013) (PubMed).

Aliases for PKD1 抗体

polycystin 1, transient receptor potential channel interacting (PKD1) 抗体
polycystin 1, transient receptor poteintial channel interacting (Pkd1) 抗体
polycystin 1, transient receptor potential channel interacting (Pkd1) 抗体
polycystin-1 (LOC749291) 抗体
mFLJ00285 抗体
PBP 抗体
Pc-1 抗体
PC1 抗体
TRPP1 抗体
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