Use your antibodies-online credentials, if available.
Human Polyclonal IGFBPI Primary Antibody for ELISA, WB - ABIN4321640
Sugita, Morishita, Kano, Furuya, Shiba-Ishii, Noguchi: IGFBP-1 is expressed specifically in ovarian clear cell adenocarcinoma. in Histopathology 2011
Human Polyclonal IGFBPI Primary Antibody for IHC, IHC (p) - ABIN4321641
Bachmann, Burté, Pramana, Conte, Brown, Orimadegun, Ajetunmobi, Afolabi, Akinkunmi, Omokhodion, Akinbami, Shokunbi, Kampf, Pawitan, Uhlén, Sodeinde, Schwenk, Wahlgren, Fernandez-Reyes, Nilsson: Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria. in PLoS pathogens 2014
Human Monoclonal IGFBPI Primary Antibody for ELISA, WB - ABIN259029
Logan, Ponnampalam, Rahnama, Lobie, Mitchell: The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells. in Human reproduction (Oxford, England) 2010
hypoxia causes PGC (显示 PGC 抗体) migration defect by inhibiting IGF signaling through the induction of IGFBP-1
The insulin-like growth factor binding protein 1 (29-31kDa)is similarities to mammalian.
HIF-1 (显示 HIF1A 抗体) mediates hypoxia-induced IGFBP-1 gene expression in early development by selectively interacting with the hypoxia response elements and its adjacent HIF-1 (显示 HIF1A 抗体) ancillary sequence.
TGE (显示 TGM3 抗体) duplicated IGFBP-1 may provide additional flexibility in fine-tuning insulin (显示 INS 抗体)-like growth factor signaling activities under hypoxia and other catabolic conditions.
IGF2, IGF binding protein 1, and matrix metalloproteinases 2 and 9 in implantation-stage endometrium following immunoneutralization of vascular endothelial growth factor (显示 VEGF 抗体) in the rhesus monkey.
association between serum IGFBP-1 and IGF-I (显示 IGF1 抗体) levels with advanced fibrosis in non-alcoholic fatty liver disease patients
we demonstrated that IGFBP-1 suppress the migration of BGC-823 gastric cancer cells and play a protective role in the process of H. pylori-induced gastric cancer.
These data support the hypothesis that down regulation of the insulin (显示 INS 抗体)-like growth factor (IGF-I (显示 IGF1 抗体)) signaling links decidual phosphorylated insulin (显示 INS 抗体)-like growth factor-binding protein (IGFBP-1) hyperphosphorylation to restricted fetal growth in placental insufficiency.
There was underexpression of the majority of genes after sunitinib treatment. The lower expression levels of IGFBP1, CCL20 (显示 CCL20 抗体), CXCL6 and FGB (显示 FGB 抗体) were confirmed by qRT-PCR in all cases. The downregulation of gene expression leads us to search for methylation as a mechanism of action of the tyrosine kinase (显示 TXK 抗体) inhibitors
A panel consisting of IGFBP1, KIM1 (显示 HAVCR1 抗体), GCLC (显示 GCLC 抗体) and GSTM1 (显示 GSTM1 抗体) genes could be used in combination for early screening of CKDu, whereas these genes in addition with FN1 (显示 FN1 抗体), IGFBP3 (显示 IGFBP3 抗体) and KLK1 (显示 KLK1 抗体) could be used to monitor progression of CKDu. The regulation of these genes has to be studied on larger populations to validate their efficiency for further clinical use.
NR4A modulates the decidualization of hESCs by upregulating prolactin (PRL (显示 PRL 抗体)) and insulin-like growth factor binding protein-1 (IGFBP-1) expression and transformation in vitro.
We report interactions between CSNK (显示 CSN3 抗体)-2beta and IGFBP-1 as well as mTOR (显示 FRAP1 抗体) and CSNK (显示 CSN3 抗体)-2beta, providing strong evidence of a mechanistic link between mTOR (显示 FRAP1 抗体) and IGF-I (显示 IGF1 抗体) signaling, two critical regulators of cell growth via CSNK (显示 CSN3 抗体)-2.
IGFBP-1 had a positive linear relation to fracture risk, partly mediated by bone mineral density (BMD (显示 BEST1 抗体)) but not related to IGF-I (显示 IGF1 抗体) or BMD (显示 BEST1 抗体)
We conclude that low BDNF (显示 BDNF 抗体) and high LCN2 (显示 LCN2 抗体) and NF-L (显示 NEFL 抗体) levels are associated with Multiple Sclerosis (MS) pathogenesis, and high IGFBP1level is a biomarker for female MS only, suggesting different MS progression pathways between the sexes. LCN2 (显示 LCN2 抗体) is a candidate predictor of response to natalizumab treatment, and NF-L (显示 NEFL 抗体) is a candidate predictor of clinically isolated syndrome's (CIS (显示 CISH 抗体)) conversion into MS.
Results show that IGFBP-1 transcription and FoxO1 (显示 FOXO1 抗体) expression are dysregulated in tamoxifen-resistant cancer cells.
In inflamed experimental autoimmune encephalomyelitis (EAE) spinal cord, study found a significant increased number of IGF-I expressing neurons versus a reduced number of IGFBP-1 positive neurons. Moreover, while nearly all IGF-I neurons expressed GSK3beta, some expressed it more intensely.
the hepatokine IGFBP1 is a critical liver-bone hormonal relay that promotes osteoclastogenesis and bone resorption as well as an essential mediator of FGF21 (显示 FGF21 抗体)-induced bone loss
Data suggest expression of Igfbp1 in liver is regulated by dietary factors; carnosine supplementation down-regulates expression of Igfbp1 in liver of obese/diabetic mice; mechanism involves suppression of Hif1a (hypoxia inducible factor 1 alpha (显示 HIF1A 抗体)).
During the two week starvation period, both the levels of plasma IGF-1 (显示 IGF1 抗体) and IGFBP-1 decreased.
These results show that RTEF-1 (显示 TEAD4 抗体)-stimulated IGFBP-1 expression may be central to the mechanism by which RTEF-1 (显示 TEAD4 抗体) attenuates blood glucose levels.
Global deletion of Igfbp1 in a c-Myc (显示 MYC 抗体) transgenic model did not accelerate the development of prostate cancer. Global Igfbp1 deletion did result in a significant increase in body weight and body fat mass.
IGFBP-1 functions as a critical hepatic survival factor in the liver by reducing the level of proapoptotic signals
IGFBP-1 may support liver regeneration at least in part via its effect on MAPK/ERK (显示 MAPK1 抗体) and C/EBP beta (显示 CEBPB 抗体) activities. These findings are the first demonstration of the involvement of IGFBP-1 in the regulation of in vivo mitogenic signaling pathways.
Induction of IFGBP1 expression by amino acid deprivation of HepG2 hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3'UTR (显示 UTS2R 抗体).
high concentrations of circulating IGFBP-1 are sufficient to cause fetal growth restriction in an animal model
Allantoic fluid levels of IGFBP-1 were increased in nuclear transfer pregnancies
IGFBP1 is a common endometrial marker of conceptus elongation in sheep and cattle and most likely regulates conceptus elongation by stimulating migration and attachment of the trophectoderm
Results of fluorescence in situ and radiation hybrid (RH) mapping assigned this gene to porcine chromosome (SSC (显示 CYP11A1 抗体)) 18q24-qter.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
insulin-like growth factor binding protein 1
, insulin-like growth factor binding protein-1
, IGF-binding protein 1
, alpha-pregnancy-associated endometrial globulin
, amniotic fluid binding protein
, binding protein-25
, binding protein-26
, binding protein-28
, growth hormone independent-binding protein
, insulin-like growth factor-binding protein 1
, placental protein 12
, INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1)