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抗Mouse (Murine) SLC25A10 抗体:
抗Human SLC25A10 抗体:
抗Rat (Rattus) SLC25A10 抗体:
Slc25a10 plays an important role in supplying malate for citrate transport required for fatty acid synthesis and its inhibition might effectively reduce lipid accumulation in adipose tissues
Study report the first recessive mutations of SLC25A10 associated to an inherited severe mitochondrial neurodegenerative disorder. We propose that SLC25A10 loss-of-function causes pathological disarrangements in respiratory-demanding conditions and oxidative stress vulnerability.
study identifies novel genes associated with insulin sensitivity in adipocytes in women independently of obesity. KFL15 and SLC25A10 are inhibitors of insulin-stimulated lipogenesis under conditions when glucose transport is the rate limiting step
the SLC25A10 carrier plays an important role in regulating redox homeostasis to protect confluent cells against oxidative stress.
Compares and contrasts all the known human SLC25A* genes and includes functional information.
SLC25A10 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
dicarboxylate ion carrier
, mitochondrial dicarboxylate carrier
, solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 10
, solute carrier family 25 member 10
, dicarboxylate transporter), member 10