MLH3 抗体
(MutL Homolog 3 (MLH3))
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].
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Latest Publications for our MLH3 抗体
: "MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability." in: Nature genetics, Vol. 24, Issue 1, pp. 27-35, (2000) (PubMed).Aliases for MLH3 抗体
mutL homolog 3 (Mlh3) 抗体mutL homolog 3 L homeolog (mlh3.L) 抗体
mutL homolog 3 (MLH3) 抗体
mutL homolog 3 (mlh3) 抗体
AV125803 抗体
BB126472 抗体
HNPCC7 抗体
MGC80774 抗体
MLH3 抗体
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