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MKNK2 抗体

(MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2))
This gene encodes a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization. [provided by RefSeq, Aug 2011].
MKNK2 抗体  (AA 1-158) MKNK2 抗体  (AA 1-158) MKNK2 抗体 (AA 1-158) (ABIN516167)

MKNK2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2A10 unconjugated

MKNK2 抗体  (AA 1-158) MKNK2 抗体  (AA 1-158) MKNK2 抗体 (AA 1-158) (ABIN516166)

MKNK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F11 unconjugated

MKNK2 抗体  (AA 36-85) MKNK2 抗体  (AA 36-85) MKNK2 抗体 (AA 36-85) (ABIN6744440)

MKNK2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 斑马鱼, Bat, 猴, Pig WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated

MKNK2 抗体 by 适用

Find MKNK2 抗体 for a variety of species such as anti-Human MKNK2, anti-Mouse MKNK2, anti-Rat MKNK2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find MKNK2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find MKNK2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find MKNK2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MKNK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (7)
Cat. No. ABIN516167
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
Cat. No. ABIN516166
Quantity 100 μg
Datasheet Datasheet

Application WB, IHC (p), IHC
Validations
  • (3)
Cat. No. ABIN6744440
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN516164
Quantity 50 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN5675314
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7187332
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN561116
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN516165
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3185609
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN545517
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN391228
Quantity 400 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN5675315
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6977566
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6976705
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6978427
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our MKNK2 抗体

Scheper, Parra, Wilson, Van Kollenburg, Vertegaal, Han, Proud: "The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5692-705, (2003) (PubMed).

Scheper, Morrice, Kleijn, Proud: "The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells." in: Molecular and cellular biology, Vol. 21, Issue 3, pp. 743-54, (2001) (PubMed).

Knauf, Tschopp, Gram: "Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2." in: Molecular and cellular biology, Vol. 21, Issue 16, pp. 5500-11, (2001) (PubMed).

Aliases for MKNK2 抗体

MAP kinase interacting serine/threonine kinase 2 (MKNK2) 抗体
MAP kinase interacting serine/threonine kinase 2 (mknk2) 抗体
MAP kinase-interacting serine/threonine kinase 2 (Mknk2) 抗体
MAP kinase interacting serine/threonine kinase 2b (mknk2b) 抗体
MAP kinase interacting serine/threonine kinase 2 L homeolog (mknk2.L) 抗体
MAP kinase interacting serine/threonine kinase 2 (Mknk2) 抗体
MAP kinase interacting serine/threonine kinase 2a (mknk2a) 抗体
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