Mitogen-Activated Protein Kinase Kinase 4 抗体
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
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| MAP2K4 抗体 | 人 | 小鼠 Monoclonal |
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| MAP2K4 抗体 | 人 | 小鼠 Monoclonal |
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| MAP2K4 抗体 | 人 | 小鼠 Monoclonal |
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| MAP2K4 抗体 | 人 | 小鼠 Monoclonal |
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| MAP2K4 抗体 (AA 137-394) | 人 | 兔 Polyclonal |
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| MAP2K4 抗体 (AA 1-399) | 人 | 小鼠 Polyclonal |
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| MAP2K4 抗体 (AA 259-398) | 人 | 兔 Polyclonal |
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| MAP2K4 抗体 (pSer80) | 人 | 兔 Polyclonal |
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| MAP2K4 抗体 (pThr261) | 人 | 兔 Polyclonal |
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| MAP2K4 抗体 (pSer257, pThr261) | 人 | 兔 Polyclonal |
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| MAP2K4 抗体 (AA 235-264) | 人 | 兔 Polyclonal |
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| MAP2K4 抗体 | 人 | 小鼠 Monoclonal |
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| MAP2K4 抗体 (AA 300-399) | 人 | 兔 Polyclonal |
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| Recombinant MAP2K4 抗体 (pSer80) | 人 | 兔 Monoclonal |
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| MAP2K4 抗体 | 人 | Monoclonal |
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| MAP2K4 抗体 | 人 | 小鼠 Monoclonal |
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| MAP2K4 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MAP2K4 抗体 (AA 2-397) | 小鼠 | 兔 Polyclonal |
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| MAP2K4 抗体 (pSer80) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MAP2K4 抗体 (pThr261) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1D6
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2E4
- 标记
- unconjugated
- 抗体亚型
- IgG2b
Primary Antibody
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 4B4
- 标记
- unconjugated
- 抗体亚型
- IgG2a
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
2 references - 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5H4
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 137-394
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-399
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 259-398
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer80
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pThr261
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer257, pThr261
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB11276
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 235-264
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2D10D8
- 标记
- unconjugated
- 抗体亚型
- IgM
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
KO 验证
- 质量等级
- KO Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 300-399
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 25GB4635
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- pSer80
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 2-397
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pSer80
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pThr261
Latest Publications for our Mitogen-Activated Protein Kinase Kinase 4 抗体
: "Microarray Analysis Identifies the Potential Role of Long Non-Coding RNA in Regulating Neuroinflammation during Japanese Encephalitis Virus Infection." in: Frontiers in immunology, Vol. 8, pp. 1237, (2017) (PubMed).
: "High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays." in: Journal of proteome research, Vol. 12, Issue 5, pp. 2311-20, (2013) (PubMed).
: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).
: "How does arrestin assemble MAPKs into a signaling complex?" in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 685-95, (2008) (PubMed).
: "Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines." in: Molecular cancer research : MCR, Vol. 6, Issue 3, pp. 501-8, (2008) (PubMed).
: "siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle." in: Diabetes, Vol. 57, Issue 8, pp. 2066-73, (2008) (PubMed).
: "Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3252-8, (2008) (PubMed).
: "Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 3507-19, (2007) (PubMed).
: "RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation." in: The Journal of biological chemistry, Vol. 282, Issue 20, pp. 14788-96, (2007) (PubMed).
: "Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases." in: Journal of cancer research and clinical oncology, Vol. 131, Issue 3, pp. 191-8, (2005) (PubMed).
: "High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays." in: Journal of proteome research, Vol. 12, Issue 5, pp. 2311-20, (2013) (PubMed).
: "Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma." in: PLoS ONE, Vol. 7, Issue 1, pp. e30215, (2012) (PubMed).
: "How does arrestin assemble MAPKs into a signaling complex?" in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 685-95, (2008) (PubMed).
: "Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines." in: Molecular cancer research : MCR, Vol. 6, Issue 3, pp. 501-8, (2008) (PubMed).
: "siRNA-mediated reduction of inhibitor of nuclear factor-kappaB kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle." in: Diabetes, Vol. 57, Issue 8, pp. 2066-73, (2008) (PubMed).
: "Synoviocyte innate immune responses: I. Differential regulation of interferon responses and the JNK pathway by MAPK kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 5, pp. 3252-8, (2008) (PubMed).
: "Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 3507-19, (2007) (PubMed).
: "RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation." in: The Journal of biological chemistry, Vol. 282, Issue 20, pp. 14788-96, (2007) (PubMed).
: "Reduced metastasis-suppressor gene mRNA-expression in breast cancer brain metastases." in: Journal of cancer research and clinical oncology, Vol. 131, Issue 3, pp. 191-8, (2005) (PubMed).
Aliases for Mitogen-Activated Protein Kinase Kinase 4 抗体
mitogen-activated protein kinase kinase 4 (MAP2K4) 抗体mitogen-activated protein kinase kinase 4 (Map2k4) 抗体
mitogen-activated protein kinase kinase 4a (map2k4a) 抗体
mitogen-activated protein kinase kinase 4 (map2k4) 抗体
MAP kinase kinase 4 (Mkk4) 抗体
mitogen activated protein kinase kinase 4 (Map2k4) 抗体
mitogen-activated protein kinase kinase 4 (MKK4) 抗体
mitogen-activated protein kinase kinase 4b (map2k4b) 抗体
142758_at 抗体
ARABIDOPSIS THALIANA MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 抗体
ATMEK4 抗体
ATMKK4 抗体
CG9738 抗体
CT27508 抗体
D-MKK4 抗体
Dmel\\CG9738 抗体
DMKK4 抗体
dMKK4 抗体
dMkk4 抗体
F19C24.26 抗体
F19C24_26 抗体
hep 抗体
JNKK 抗体
jnkk 抗体
JNKK1 抗体
jnkk1 抗体
JNKK2 抗体
map2k4 抗体
MAP KINASE KINASE 4 抗体
MAPKK4 抗体
mapkk4 抗体
MEK4 抗体
mek4 抗体
mitogen-activated protein kinase kinase 4 抗体
MKK4 抗体
mkk4 抗体
MKK4A-l 抗体
MKK4B 抗体
Mpk4 抗体
PRKMK4 抗体
prkmk4 抗体
SAPKK-1 抗体
SAPKK1 抗体
SEK1 抗体
Sek1 抗体
sek1 抗体
SEK1/MKK4 抗体
SERK1 抗体
Serk1 抗体
serk1 抗体
SKK1 抗体
xmek2 抗体
zgc:136500 抗体
zgc:194486 抗体
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