Mitogen-Activated Protein Kinase Kinase 2 抗体
(Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant MEK2 抗体 | 人 | 兔 Monoclonal |
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| MEK2 抗体 (AA 1-45) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Rockland Original | MEK2 抗体 (N-Term) | 人, 小鼠 | 兔 Polyclonal |
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| MEK2 抗体 (pThr394) | 人, 猴 | 兔 Polyclonal |
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| MEK2 抗体 (pThr394) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Rockland Original | MEK2 抗体 (N-Term) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
|
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| Rockland Original | MEK2 抗体 (C-Term) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| MEK2 抗体 (AA 2-200) | 人 | 兔 Polyclonal |
|
|
|
| MEK2 抗体 (AA 1-400) (Biotin) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
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| MEK2 抗体 (AA 1-400) (Biotin) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| MEK2 抗体 (AA 1-400) (HRP) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| MEK2 抗体 (AA 1-400) (Biotin) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
|
|
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| MEK2 抗体 (AA 1-400) (HRP) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
|
|
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| MEK2 抗体 (AA 1-400) (HRP) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| MEK2 抗体 (AA 1-45) (Biotin) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MEK2 抗体 (AA 1-45) (HRP) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MEK2 抗体 (Thr394) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| MEK2 抗体 (AA 1-400) (APC) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MEK2 抗体 (AA 1-45) (APC) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| MEK2 抗体 (AA 1-400) (APC) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-45
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- Supplier Product No.
- Rockland 600-401-gn8
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Rockland Original
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- pThr394
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 261-310, pThr394
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- Supplier Product No.
- Rockland 200-301-gn8
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 19G10-F1-E2
- 标记
- unconjugated
- 抗体亚型
- IgG2b kappa
- 抗原表位
- N-Term
Rockland Original
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- Supplier Product No.
- Rockland 200-301-gq2
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 12A6-G1-G11
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- C-Term
Rockland Original
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2B4
- 标记
- Biotin
- 抗体亚型
- IgG2b
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2B4
- 标记
- HRP
- 抗体亚型
- IgG2b
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2H4
- 标记
- Biotin
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2H4
- 标记
- HRP
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 1-45
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 1-45
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Thr394
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-400
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- AA 1-45
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2H4
- 标记
- APC
- 抗体亚型
- IgG1
- 抗原表位
- AA 1-400
Latest Publications for our Mitogen-Activated Protein Kinase Kinase 2 抗体
: "Follicular fluid meiosis-activating sterol (FF-MAS) promotes meiotic resumption via the MAPK pathway in porcine oocytes." in: Theriogenology, (2019) (PubMed).
: "The MEK/ERK cascade: from signaling specificity to diverse functions." in: Biochimica et biophysica acta, Vol. 1773, Issue 8, pp. 1213-26, (2007) (PubMed).
: "Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18574-9, (2006) (PubMed).
: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, (2003) (PubMed).
: "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7177-88, (2003) (PubMed).
: "p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2." in: Cancer research, Vol. 63, Issue 13, pp. 3473-7, (2003) (PubMed).
: "The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13663-71, (2003) (PubMed).
: "The MEK/ERK cascade: from signaling specificity to diverse functions." in: Biochimica et biophysica acta, Vol. 1773, Issue 8, pp. 1213-26, (2007) (PubMed).
: "Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 49, pp. 18574-9, (2006) (PubMed).
: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, (2003) (PubMed).
: "Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7177-88, (2003) (PubMed).
: "p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1,2." in: Cancer research, Vol. 63, Issue 13, pp. 3473-7, (2003) (PubMed).
: "The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 13663-71, (2003) (PubMed).
Aliases for Mitogen-Activated Protein Kinase Kinase 2 抗体
mitogen-activated protein kinase kinase 2 (MAP2K2) 抗体mitogen-activated protein kinase kinase 2 (Map2k2) 抗体
mitogen activated protein kinase kinase 2 (Map2k2) 抗体
MAP kinase kinase 2 (MKK2) 抗体
mitogen-activated protein kinase kinase 2a (map2k2a) 抗体
mitogen-activated protein kinase kinase 2b (map2k2b) 抗体
AA589381 抗体
ATMKK2 抗体
CFC4 抗体
F27B13.50 抗体
F27B13_50 抗体
map2k2 抗体
MAP KINASE KINASE 1 抗体
MAP kinase kinase 2 抗体
MAPKK2 抗体
MEK2 抗体
MK1 抗体
MK2 抗体
MKK2 抗体
PRKMK2 抗体
Prkmk2 抗体
wu:fa56c06 抗体
zgc:123171 抗体
zgc:172250 抗体
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