MEK2 抗体 (pThr394)
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Quick Overview for MEK2 抗体 (pThr394) (ABIN1531905)
抗原
See all MEK2 (MAP2K2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 261-310, pThr394
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原理
- MEK-2 (phospho Thr394) Antibody
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特异性
- Phospho-MEK-2 (T394) Polyclonal Antibody detects endogenous levels of MEK-2 protein only when phosphorylated at T394.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MEK2 around the phosphorylation site of Thr394. AA range:261-310
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-50) antibody
MAP2K2 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-50) antibodyMAP2K2 适用: 人, 小鼠 WB, IHC, IP, FACS, ICC 宿主: 兔 Monoclonal BLR079G unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 200-229) antibodyMAP2K2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12322 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 44-313) antibodyMAP2K2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 262-292) antibodyMAP2K2 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB3597 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) antibodyMAP2K2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-30), (N-Term) antibodyMAP2K2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal RB3595 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-100) antibodyKO Validated MAP2K2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-360) antibodyMAP2K2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 8D10 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2) (AA 1-400) antibodyMAP2K2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 μg:mg lysate. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
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别名
- MEK2
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背景
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Synonyms: MAP2K2, MEK2, MKK2, PRKMK2, Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008],
Gene Name: MAP2K2
Protein Name: Dual specificity mitogen-activated protein kinase kinase 2
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分子量
- 44 kDa
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基因ID
- 5606
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OMIM
- 115150
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UniProt
- P36507
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途径
- MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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