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MECP2 蛋白

(Methyl CpG Binding Protein 2 (MECP2))
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009].
Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (GST tag) Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (GST tag) Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (GST tag) (ABIN6923004)

MECP2 宿主: 人 宿主: 小麦胚 Recombinant AP, AA, ELISA, WB

Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (His tag) Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (His tag) Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) protein (His tag) (ABIN3083495)

Crystallography grade MECP2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Methyl CpG Binding Protein 2 (MECP2) (AA 1-484) protein (His tag) Methyl CpG Binding Protein 2 (MECP2) (AA 1-484) protein (His tag) Methyl CpG Binding Protein 2 (MECP2) (AA 1-484) protein (His tag) (ABIN3120366)

Crystallography grade MECP2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

MECP2 蛋白 by Grade

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MECP2 蛋白 by Origin

Find MECP2 蛋白 for a variety of species such as anti-Human MECP2, anti-Mouse MECP2, anti-Rat MECP2. The species listed below are among those available. Click on a link to go to the corresponding products.

MECP2 蛋白 by Source

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MECP2 蛋白 by 蛋白类型

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MECP2 蛋白 by 应用范围

Find MECP2 蛋白 validated for a specific application such as WB, ELISA, SDS, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular MECP2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1310624
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7123936
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN1945397
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7085602
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7085601
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2746868
Quantity 5 applications
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1065539
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Cynomolgus
Source Yeast
Validations
Cat. No. ABIN1644051
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1473780
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MECP2 蛋白

Nott, Cheng, Gao, Lin, Gjoneska, Ko, Minhas, Zamudio, Meng, Zhang, Jin, Tsai: "Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior." in: Nature neuroscience, Vol. 19, Issue 11, pp. 1497-1505, (2016) (PubMed).

Aliases for MECP2 蛋白

methyl-CpG binding protein 2 (MECP2) 蛋白
methyl CpG binding protein 2 (Mecp2) 蛋白
methyl CpG binding protein 2 (mecp2) 蛋白
methyl-CpG binding protein 2 S homeolog (mecp2.S) 蛋白
1500041B07Rik 蛋白
AUTSX3 蛋白
BB130002 蛋白
D630021H01Rik 蛋白
Mbd5 蛋白
MRX16 蛋白
MRX79 蛋白
MRXS13 蛋白
MRXSL 蛋白
PPMX 蛋白
RS 蛋白
RTS 蛋白
RTT 蛋白
WBP10 蛋白
wu:fk96a04 蛋白
zgc:111857 蛋白
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