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MECP2 Protein (AA 1-486) (His tag)

MECP2 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1945397
发货至: 中国
  • 抗原 See all MECP2 蛋白
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-486
    宿主
    • 8
    • 3
    • 2
    • 1
    资源
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This MECP2 protein is labelled with His tag.
    原理
    Recombinant Human Methyl-CpG-Binding Protein 2/MECP2 (C-6His)
    序列
    MVAGMLGLRE EKSEDQDLQG LKDKPLKFKK VKKDKKEEKE GKHEPVQPSA HHSAEPAEAG KAETSEGSGS APAVPEASAS PKQRRSIIRD RGPMYDDPTL PEGWTRKLKQ RKSGRSAGKY DVYLINPQGK AFRSKVELIA YFEKVGDTSL DPNDFDFTVT GRGSPSRREQ KPPKKPKSPK APGTGRGRGR PKGSGTTRPK AATSEGVQVK RVLEKSPGKL LVKMPFQTSP GGKAEGGGAT TSTQVMVIKR PGRKRKAEAD PQAIPKKRGR KPGSVVAAAA AEAKKKAVKE SSIRSVQETV LPIKKRKTRE TVSIEVKEVV KPLLVSTLGE KSGKGLKTCK SPGRKSKESS PKGRSSSASS PPKKEHHHHH HHSESPKAPV PLLPPLPPPP PEPESSEDPT SPPEPQDLSS SVCKEEKMPR GGSLESDGCP KEPAKTQPAV ATAATAAEKY KHRGEGERKD IVSSSMPRPN REEPVDSRTP VTERVSVDHH HHHH
    产品特性
    Recombinant Human MECP2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 1-486) of Human MECP2 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product MECP2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    别名
    MECP2 (MECP2 产品)
    别名
    AUTSX3 Protein, MRX16 Protein, MRX79 Protein, MRXS13 Protein, MRXSL Protein, PPMX Protein, RS Protein, RTS Protein, RTT Protein, 1500041B07Rik Protein, BB130002 Protein, D630021H01Rik Protein, Mbd5 Protein, WBP10 Protein, wu:fk96a04 Protein, zgc:111857 Protein, methyl-CpG binding protein 2 Protein, methyl CpG binding protein 2 Protein, methyl-CpG binding protein 2 S homeolog Protein, MECP2 Protein, Mecp2 Protein, mecp2 Protein, mecp2.S Protein
    背景
    The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may also be necessary for the function of other types of brain cells.
    分子量
    53.5 kDa
    UniProt
    P51608
    途径
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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