MCM10 蛋白
(Minichromosome Maintenance Deficient 10 (MCM10))
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
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custom-made
MCM10
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MCM10
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
MCM10
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
ELISA, WB
Aliases for MCM10 蛋白
Minichromosome maintenance 10 (Mcm10) 蛋白minichromosome maintenance 10 replication initiation factor (MCM10) 蛋白
minichromosome maintenance 10 replication initiation factor (Mcm10) 蛋白
minichromosome maintenance 10 replication initiation factor L homeolog (mcm10.L) 蛋白
2410041F14Rik 蛋白
AU018508 蛋白
C79164 蛋白
C330019M07Rik 蛋白
CG9241 蛋白
CNA43 蛋白
Dmel\\CG9241 蛋白
DmMCM10 蛋白
DNA43 蛋白
mcm10 蛋白
Scim19 蛋白
xmcm10 蛋白
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