LILRB2 抗体
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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41 results
LILRB2
适用: 人
ELISA, FACS, BLI, Func, SPR
宿主: Human
Monoclonal
JTX-8064
unconjugated
Recombinant Antibody
Latest Publications for our LILRB2 抗体
: "Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells." in: International journal of nanomedicine, Vol. 13, pp. 6941-6960, (2018) (PubMed).: "Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4." in: Nature communications, Vol. 9, Issue 1, pp. 742, (2018) (PubMed).
: "Co-expression of ILT4/HLA-G in human non-small cell lung cancer correlates with poor prognosis and ILT4-HLA-G interaction activates ERK signaling." in: Tumour biology, Vol. 37, Issue 8, pp. 11187-98, (2017) (PubMed).
: "ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer." in: FEBS letters, Vol. 589, Issue 17, pp. 2248-56, (2015) (PubMed).
: "IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses." in: Journal of leukocyte biology, Vol. 95, Issue 1, pp. 33-46, (2014) (PubMed).
: "HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 12, pp. 6184-93, (2012) (PubMed).
: "Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 5, pp. 2110-7, (2012) (PubMed).
: "Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression." in: Cancer research, Vol. 71, Issue 2, pp. 318-27, (2011) (PubMed).
: "Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e22504, (2011) (PubMed).
: "Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 3966-76, (2011) (PubMed).
Aliases for LILRB2 抗体
leukocyte immunoglobulin-like receptor subfamily A member 3 (LOC100433990) 抗体leukocyte immunoglobulin like receptor B2 (LILRB2) 抗体
CD85D 抗体
ILT-4 抗体
ILT4 抗体
LIR-2 抗体
LIR2 抗体
MIR-10 抗体
MIR10 抗体
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