LILRB2 抗体 (C-Term)
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- 抗原 See all LILRB2 抗体
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LILRB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MDTRAAASEA PQDVTYAQLH SLTLRRKATE PPPSQEREPP AEPSIYATLA
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against LILRB2. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product LILRB2 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 598 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- 别名
- LILRB2 (LILRB2 产品)
- 别名
- CD85D antibody, ILT-4 antibody, ILT4 antibody, LIR-2 antibody, LIR2 antibody, MIR-10 antibody, MIR10 antibody, leukocyte immunoglobulin-like receptor subfamily A member 3 antibody, leukocyte immunoglobulin like receptor B2 antibody, LOC100433990 antibody, LILRB2 antibody
- 背景
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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD85D, ILT4, LILRA6, LIR-2, LIR2, MIR-10, MIR10
Protein Interaction Partner: PTPN6, FCGR1A, HLA-F, HLA-G, HLA-C, HLA-B, HLA-A,
Protein Size: 598 - 分子量
- 65 kDa
- 基因ID
- 10288
- NCBI登录号
- NM_005874, NP_005865
- UniProt
- Q8N423
- 途径
- Cellular Response to Molecule of Bacterial Origin
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