Klotho 蛋白
(Klotho (KL))
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008].
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Latest Publications for our Klotho 蛋白
: "The function of miR-199a-5p/Klotho regulating TLR4/NF-?B p65/NGAL pathways in rat mesangial cells cultured with high glucose and the mechanism." in: Molecular and cellular endocrinology, Vol. 417, pp. 84-93, (2015) (PubMed).
Aliases for Klotho 蛋白
klotho (KL) 蛋白klotho (Kl) 蛋白
Klotho (Kl) 蛋白
klotho (kl) 蛋白
klotho (LOC100533542) 蛋白
alpha-kl 蛋白
KL 蛋白
LOC100223456 蛋白
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