Hepatitis B Virus E Antigen (HBeAg) ELISA 试剂盒
HBeAg
适用: Hepatitis B Virus (HBV)
Colorimetric
Sandwich ELISA
Serum
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- 抗原 See all Hepatitis B Virus E Antigen (HBeAg) ELISA试剂盒
- Hepatitis B Virus E Antigen (HBeAg)
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适用
- Hepatitis B Virus (HBV)
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- This enzyme-linked immunosorbent assay (ELISA) kit is for the qualitative detection of hepatitis B virus e antigen (HBeAg) in human serum or plasma.
- 样品类型
- Serum
- Analytical Method
- Qualitative
- 特异性
- 99%
- 灵敏度
- 99%
- Top Product
- Discover our top product HBeAg ELISA Kit
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- 样本量
- 50 μL
- 实验时间
- 1 - 2 h
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
- 有效期
- 12-18 months
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- 抗原 See all Hepatitis B Virus E Antigen (HBeAg) ELISA试剂盒
- Hepatitis B Virus E Antigen (HBeAg)
- Abstract
- HBeAg 产品
- 别名
- precore; HBe antigen; PreC; HBeAg; precore protein; external core antigen; HBeAg; p25 ELISA Kit, C ELISA Kit
- 物质类
- Viral Protein
- 背景
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Hepatitis B virus (HBV) is an enveloped, double- stranded DNA virus belonging to the Hepadnaviridae family and is recognized as the major cause of blood transmitted hepatitis together with hepatitis C virus (HCV). Infection with HBV induces a spectrum of clinical manifestations ranging from mild, inapparent disease to fulminant hepatitis, severe chronic liver disease, which in some cases can lead to cirrhosis and carcinoma of the liver. Classification of a hepatitis B infection requires the identification of several serological markers expressed during three phases (incubation, acute and convalescent) of the infection. Now several diagnostic test are used for screening, clinical diagnosis and management of the disease.
Hepatitis B “e” antigen is a virus protein to be intimately associated with hepatitis B virus replication, indicating high degree of infectivity. HBeAg appears shortly after HBsAg and is detectable for few days to several weeks. During treatment and recovery, the titer of HBeAg declines and is replaced by the corresponding antibody (anti-HBe). In chronic hepatitis B infections, elevated levels of HBeAg can be detected for years, which is a marker for large quantity of virus. In some chronic HBsAg positive patients, HBeAg is undetectable due to HBV mutations suggesting for low level of viral replication. If HBeAg is considered a specific marker of infectivity, the presence of anti-HBeAg antibody in blood is recognized to be a clinical sign of recovery from the infection.
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