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MERTK ELISA 试剂盒

MERTK 适用: 小鼠 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Cell Culture Lysate, Cell Culture Supernatant, Serum, Tissue Homogenate
产品编号 ABIN6719882
发货至: 中国
  • 抗原 See all MERTK ELISA试剂盒
    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
    适用
    • 5
    • 2
    • 1
    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    78 pg/mL - 5000 pg/mL
    最低检测浓度
    78 pg/mL
    应用范围
    ELISA
    原理
    Sandwich ELISA for Quantitative Detection of Antigen
    样品类型
    Cell Culture Lysate, Cell Culture Supernatant, Serum, Tissue Homogenate
    Analytical Method
    Quantitative
    产品特性

    Synonyms: C mer, c mer proto oncogene tyrosine kinase, MER receptor tyrosine kinase, Mertk, MERTK_HUMAN, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, RP38, STK kinase, Tyrosine-protein kinase Mer

    Background: Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium(RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors(TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

    Gene Name: MERTK

    Production: Natural and recombinant mouse MER. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: sf21, Immunogen sequence: E23-F498

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    Discover our top product MERTK ELISA Kit
  • 应用备注

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 313pg/mL, 156pg/mL, 78pg/mL mouse MER standard solutions into the pre-coated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernates, cell lysates, tissue homogenates or serum to each empty well. We recommend that each mouse MER standard solution and each sample is measured in duplicate.

    ELISA Dilution: 78pg/mL-5000pg/mL

    样本量
    100 μL
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • 抗原 See all MERTK ELISA试剂盒
    MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
    别名
    MER - MERTK (MERTK 产品)
    基因ID
    17289
    NCBI登录号
    NP_032613
    UniProt
    Q60805
    途径
    RTK signaling
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