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D-Dimer ELISA 试剂盒

适用: 小鼠 Colorimetric Competition ELISA 0.617 ng/mL - 50 ng/mL Plasma
产品编号 ABIN6200196
发货至: 中国
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    D-Dimer
    适用
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    小鼠
    检测方法
    Colorimetric
    实验类型
    Competition ELISA
    检测范围
    0.617 ng/mL - 50 ng/mL
    最低检测浓度
    0.617 ng/mL
    应用范围
    ELISA
    原理
    The D-Dimer ELISA Kit from Abbexa is able to quantitatively determine the D-Dimer levels in murine plasma samples. The kit offers high sensitivity; it is able to differ between concentration levels of less than < 0.244 ng/mL. Only 0.5 µl of mouse plasma sample is sufficient for D-Dimer level determination. A 100-fold sample dilution is advised, the broad detection range from 0.617 ng/mL to 50 ng/mL will reliable capture the plasma level. Three levels of QC ensure and maintain a high quality production process.
    样品类型
    Plasma
    Analytical Method
    Quantitative
    灵敏度
    < 0.244 ng/mL
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    Discover our top product D-Dimer ELISA Kit
  • 应用备注

    Stability: The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5 % within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

    Recommended dilutions: Optimal dilutions/concentrations should be determined by the end user.

    Standard Form: Lyophilized

    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C/-20 °C
    储存方法
    Upon receipt, store the kit according to the storage instruction in the kit's manual.
    有效期
    6 months
  • Cheng, Liu, Ma, Liu, Xin, Jia, Chen, Li, Sun: "Prothrombotic effects of high uric acid in mice via activation of MEF2C-dependent NF-κB pathway by upregulating let-7c." in: Aging, Vol. 12, Issue 18, pp. 17976-17989, (2020) (PubMed).

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    D-Dimer
    Abstract
    D-Dimer 产品
    背景

    D-dimers emerge during fibrinolysis as a degradation product of fibrin. The circulating enzyme plasmin cleaves the fibrin gel in a number of places, in order to prevent blood clots from accumulating to a problematic size. However the cross-link between two D fragments remains intact. The structure of D-dimer is either a 180 kDa or 195 kDa molecule of two D domains, or a 340 kDa molecule of two D domains combined with one E domain of the original fibrinogen molecule.

    In clinical diagnostic the D-dimer concentration is an indicator for thrombosis. D-dimer is relevant to research into thrombosis, with common target including fibrinogen, fibrin degradation product, plasminogen activity.

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