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FASL ELISA 试剂盒

This 大鼠 FASL ELISA Kit is a Colorimetric ELISA Kit designed to quantify 大鼠 FASL.

产品编号 ABIN2042459

发货至: 中国

Quick Overview for FASL ELISA 试剂盒 (ABIN2042459)

抗原

See all FASL ELISA试剂盒

FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

适用

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大鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

31.2-2000 pg/mL

应用范围

ELISA

Discover our top product FASL ELISA Kit

最低检测浓度

31.2 pg/mL

交叉反应（详细）

There is no detectable cross-reactivity with other relevant proteins.

灵敏度

< 10 pg/mL

组件

96-well plate pre-coated with anti-FAS-L, Rat
Lyophilized recombinant FAS-L, Rat standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Fas Ligand (TNF Superfamily, Member 6) (FASL) ELISA Kit
FASL 适用: 小鼠 AA 132-279 Colorimetric Sandwich ELISA 31.2-2000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum

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Human CD178 / Fas-Ligand ELISpot Kit
ELISpot 适用: 人 Without plate

Human CD178 / Fas-Ligand ELISpot Kit
ELISpot 适用: 人 Pre-coated

Human CD178 / Fas-Ligand ELISpot Kit
ELISpot 适用: 人 Non-sterile plate

板类型

Pre-coated

实验流程

Sandwich ELISA quantitative detection kit for Rat FAS-L in cell culture supernates, serum and plasma (heparin, EDTA, citrate).FAS Ligand (FASL) is a 40kD type II membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, Fas. The human FasL gene consists of approximately 8.0 kb and is split into four exons. This gene consists of 281 amino acids with a calculated M(r) of 31,759 and was mapped on chromosome 1q23. It has an identity of 76.9% at the amino acid sequence level with mouse FasL. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis. This system may also play a role in modulating the genetic susceptibility of mouse strains to develop T-cell lymphoblastic lymphomas.

限制

仅限研究用
储存条件

4 °C/-20 °C
抗原 See all FASL ELISA试剂盒

FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

别名

FAS-L

基因ID

25385

UniProt

P36940

途径

Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity

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