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FASL ELISA 试剂盒

小鼠 FASL ELISA Kit, Colorimetric is an assay for quantification of 小鼠 FASL.
产品编号 ABIN2042458
发货至: 中国
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Quick Overview for FASL ELISA 试剂盒 (ABIN2042458)

抗原

See all FASL ELISA试剂盒
FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

适用

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小鼠

检测方法

Colorimetric

实验类型

Sandwich ELISA

检测范围

15.6-1000 pg/mL

应用范围

ELISA
  • 最低检测浓度

    15.6 pg/mL

    交叉反应 (详细)

    There is no detectable cross-reactivity with other relevant proteins.

    灵敏度

    < 10 pg/mL

    组件

    96-well plate pre-coated with anti-FAS-L, Mouse
    Lyophilized recombinant FAS-L, Mouse standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • 板类型

    Pre-coated

    实验流程

    Sandwich ELISA quantitative detection kit for Mouse FASL in cell culture supernates, serum and plasma (heparin, EDTA, citrate).FAS Ligand (FASL) is a 40kD type II membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, Fas. The human FasL gene consists of approximately 8.0 kb and is split into four exons. This gene consists of 281 amino acids with a calculated M(r) of 31,759 and was mapped on chromosome 1q23. It has an identity of 76.9% at the amino acid sequence level with mouse FasL. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis. This system may also play a role in modulating the genetic susceptibility of mouse strains to develop T-cell lymphoblastic lymphomas.

    限制

    仅限研究用
  • 储存条件

    4 °C/-20 °C
  • 抗原 See all FASL ELISA试剂盒

    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

    别名

    FAS-L

    基因ID

    14103

    UniProt

    P25446

    途径

    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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