KCTD11 抗体
(Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))
Plays a role as a marker and a regulator of neuronal differentiation\; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and nerve growth factor/NGFB. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. May play a role as a tumor repressor and functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1 (By similarity).
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KCTD11
适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 猴, Pig
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our KCTD11 抗体
: "REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10833-8, (2004) (PubMed).
Aliases for KCTD11 抗体
potassium channel tetramerization domain containing 11 (KCTD11) 抗体potassium channel tetramerisation domain containing 11 (Kctd11) 抗体
potassium channel tetramerization domain containing 11 (Kctd11) 抗体
AF465352 抗体
C17orf36 抗体
KCASH1 抗体
KCTD11 抗体
Ren 抗体
REN 抗体
REN/KCTD11 抗体
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