KCNMA1 产品
(Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
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MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Featured KCNMA1 Categories
Recommended KCNMA1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (3)
Cat. No.
ABIN7146334
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN3043867
Quantity
100 μg
Datasheet
Datasheet
Recommended KCNMA1 蛋白
Product
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Quantity
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Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7554321
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7563611
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1543634
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KCNMA1 Products
: "Time-course of glial changes in the hyperhomocysteinemia model of vascular cognitive impairment and dementia (VCID)." in: Neuroscience, Vol. 341, pp. 42-51, (2016) (PubMed).: "Low Na, high K diet and the role of aldosterone in BK-mediated K excretion." in: PLoS ONE, Vol. 10, Issue 1, pp. e0115515, (2015) (PubMed).
: "Evaluation of mouse urinary bladder smooth muscle for diurnal differences in contractile properties." in: Frontiers in pharmacology, Vol. 5, pp. 293, (2015) (PubMed).
: "BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 18, pp. 7082-94, (2015) (PubMed).
: "Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction." in: American journal of physiology. Cell physiology, pp. ajpcell.00127.2015, (2015) (PubMed).
: "A novel effect of thalidomide and its analogs: suppression of cereblon ubiquitination enhances ubiquitin ligase function." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2015) (PubMed).
: "Knockout of the BK ?2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity." in: The Journal of general physiology, Vol. 144, Issue 4, pp. 275-95, (2014) (PubMed).
: "BKCa channels expressed in sensory neurons modulate inflammatory pain in mice." in: Pain, Vol. 155, Issue 3, pp. 556-65, (2014) (PubMed).
: "Dynamic regulation of ?1 subunit trafficking controls vascular contractility." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 6, pp. 2361-6, (2014) (PubMed).
: "Large conductance calcium-activated potassium channels: their expression and modulation of glutamate release from nerve terminals isolated from rat trigeminal caudal nucleus and cerebral cortex." in: Neurochemical research, Vol. 39, Issue 5, pp. 901-10, (2014) (PubMed).
Synonyms and alternative names related to KCNMA1
potassium calcium-activated channel subfamily M alpha 1 (KCNMA1), calcium-activated BK potassium channel, alpha subunit (kcnma1), potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (Kcnma1), potassium calcium-activated channel subfamily M alpha 1 (Kcnma1), potassium calcium-activated channel subfamily M alpha 1 L homeolog (kcnma1.L), potassium large conductance calcium-activated channel, subfamily M, alpha member 1a (kcnma1a), calcium-activated potassium channel subunit alpha-1 (LOC100454095), slowpoke (slo), 5730414M22Rik, bA205K10.1, BcDNA:GH10751, BKCa, BKTM, bktm, CG10693, cSlo, DDBDRAFT_0190653, DDBDRAFT_0235401, DDB_0190653, DDB_0235401, Dmel\CG10693, Dslo, dSlo, dslo, dSlo1, fSlo, KCa1.1, KCNMA, Kcnma, KCNMA1, kcnma1, kcnma1-A, KCNMA1b, KCNMA1c, MaxiK, mSlo, mSLO1, mSlo1, SAKCA, sakca, si:ch211-39f22.2, SLO, Slo, SLO-ALPHA, SLO1, Slo1, slo1Protein level used designations for KCNMA1
- BK channel alpha subunit
- BKCA alpha subunit
- calcium-activated potassium channel subunit alpha-1
- calcium-activated potassium channel, subfamily M subunit alpha-1
- hSlo
- k(VCA)alpha
- maxi-K channel HSLO
- slo homolog
- slowpoke homolog
- stretch-activated Kca channel
- calcium-activated potassium channel subunit alpha 1
- BK channel
- BKCA alpha
- KCa1.1
- large conductance calcium-activated potassium channel alpha subunit
- maxi K channel
- maxiK
- rbSlo
- slo-alpha
- slo1
- calcium-activated potassium channel alpha subunit
- bSlo
- xSlo
- MaxiK calcium-activated potassium channel
- calcium activated potassium channel protein
- large conductance calcium-activated potassium (BK) channel alpha subunit a
- potassium large conductance calcium-activated channel, subfamily M, alpha member 1
- slo1a
- large conductance calcium-activated potassium channel subfamily M alpha member 1
- pulmonary calcium activated potassium channel
- calcium-activated potassium channel subunit alpha-1-like
- large calcium-activated potassium channel alpha member 1
- CG10693 gene product from transcript CG10693-RS
- CG10693-PA
- CG10693-PB
- CG10693-PC
- CG10693-PD
- CG10693-PE
- CG10693-PF
- CG10693-PH
- CG10693-PI
- CG10693-PJ
- CG10693-PK
- CG10693-PL
- CG10693-PM
- CG10693-PN
- CG10693-PO
- CG10693-PP
- CG10693-PQ
- CG10693-PR
- CG10693-PS
- CG10693-PT
- CG10693-PU
- CG10693-PV
- CG10693-PW
- CG10693-PX
- Maxi K channel
- slo-PA
- slo-PB
- slo-PC
- slo-PD
- slo-PE
- slo-PF
- slo-PH
- slo-PI
- slo-PJ
- slo-PK
- slo-PL
- slo-PM
- slo-PN
- slo-PO
- slo-PP
- slo-PQ
- slo-PR
- slo-PS
- slo-PT
- slo-PU
- slo-PV
- slo-PW
- slo-PX
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