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KCNJ5 产品

(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008].

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Featured KCNJ5 Categories

KCNJ5 抗体

High quality antibodies with extensive validation data.

KCNJ5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

KCNJ5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNJ5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN564116
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7153289
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN523031
Quantity 100 μg
Datasheet Datasheet

Recommended KCNJ5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6958697
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674766
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5674765
Quantity 96 tests
Datasheet Datasheet

Recommended KCNJ5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308450
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349493
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349492
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our KCNJ5 Products

Zhou, Shaikh, Neogi, McFarlane, Zhao, Figg, Brighton, Maniero, Teo, Azizan, Brown: "DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion." in: Hypertension (Dallas, Tex. : 1979), Vol. 65, Issue 5, pp. 1103-10, (2015) (PubMed).

Kuppusamy, Caroccia, Stindl, Bandulik, Lenzini, Gioco, Fishman, Zanotti, Gomez-Sanchez, Bader, Warth, Rossi: "A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. E1765-73, (2014) (PubMed).

Azizan, Poulsen, Tuluc, Zhou, Clausen, Lieb, Maniero, Garg, Bochukova, Zhao, Shaikh, Brighton, Teo, Davenport, Dekkers, Tops, Küsters, Ceral, Yeo, Neogi, McFarlane, Rosenfeld, Marass, Hadfield et al.: "Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. ..." in: Nature genetics, Vol. 45, Issue 9, pp. 1055-60, (2013) (PubMed).

Maita, Kitaura, Ariga, Iguchi-Ariga: "CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing." in: Experimental cell research, Vol. 303, Issue 2, pp. 375-87, (2005) (PubMed).

Synonyms and alternative names related to KCNJ5

potassium voltage-gated channel subfamily J member 5 (KCNJ5), potassium inwardly-rectifying channel, subfamily J, member 5 (Kcnj5), potassium voltage-gated channel subfamily J member 5 (Kcnj5), CIR, GIRK-4, GIRK4, KATP-1, KATP1, KIR3.4, Kir3.4, LQT13

Protein level used designations for KCNJ5

  • G protein-activated inward rectifier potassium channel 4
  • IRK-4
  • cardiac ATP-sensitive potassium channel
  • heart KATP channel
  • inward rectifier K+ channel KIR3.4
  • CIR
  • GIRK-4
  • KATP-1
  • cardiac inward rectifier
  • inward rectifier K(+) channel Kir3.4
  • potassium channel, inwardly rectifying subfamily J member 5
  • GIRK4
  • inward rectifying K channel
  • potassium inwardly-rectifying channel J5
  • Cardiac inward rectifier
  • Heart KATP channel
  • Inward rectifier K(+) channel Kir3.4
  • Potassium channel, inwardly rectifying subfamily J member 5
  • potassium inwardly-rectifying channel, subfamily J, member 5
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