KCNJ3 产品
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))
Categories
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012].
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Featured KCNJ3 Categories
KCNJ3 抗体
High quality antibodies with extensive validation data.
KCNJ3 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
KCNJ3 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KCNJ3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, IF, IHC, FACS, IHC (p)
Validations
- (6)
Cat. No.
ABIN1491310
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (2)
Cat. No.
ABIN719741
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC, ICC
Validations
- (3)
Cat. No.
ABIN6262821
Quantity
100 μL
Datasheet
Datasheet
Recommended KCNJ3 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380445
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended KCNJ3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3113708
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3120858
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3082233
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNJ3 Products
: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).: "A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. E1765-73, (2014) (PubMed).
Synonyms and alternative names related to KCNJ3
potassium voltage-gated channel subfamily J member 3 (KCNJ3), potassium inwardly-rectifying channel, subfamily J, member 3 (Kcnj3), potassium voltage-gated channel subfamily J member 3 (Kcnj3), GIRK1, girk1, Kcnf3, KGA, KIR3.1, Kir3.1Protein level used designations for KCNJ3
- G protein-activated inward rectifier potassium channel 1
- GIRK-1
- inward rectifier K(+) channel Kir3.1
- inward rectifier K+ channel KIR3.1
- potassium channel, inwardly rectifying subfamily J member 3
- potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e
- potassium inwardly-rectifying channel J3
- GIRK1
- KGA
- KGB1
- potassium channel inwarding rectifying channel subfamily J member 3
- potassium channel subunit Kir3.1 type 3 delta
- inward rectifying potassium channel, Kir3.1
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