KCNN4 产品
(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))
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The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq, Jul 2008].
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Featured KCNN4 Categories
Recommended KCNN4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, FACS
Validations
- (6)
Cat. No.
ABIN6391378
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cow, Horse, Human, Pig, Rat
Application
WB
Validations
- (6)
Cat. No.
ABIN2776147
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, FACS, ICC, IP, LCI
Validations
- (6)
Cat. No.
ABIN7044556
Quantity
100 μg
Datasheet
Datasheet
Recommended KCNN4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6219079
Quantity
96 tests
Datasheet
Datasheet
Recommended KCNN4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308477
Quantity
2 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3109946
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3132325
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNN4 Products
: "Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels." in: Frontiers in cellular neuroscience, Vol. 12, pp. 115, (2018) (PubMed).: "Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154471, (2016) (PubMed).
: "High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122992, (2015) (PubMed).
: "KCa3.1/IK1 Channel Regulation by cGMP-Dependent Protein Kinase (PKG) via Reactive Oxygen Species and CaMKII in Microglia: An Immune Modulating Feedback System?" in: Frontiers in immunology, Vol. 6, pp. 153, (2015) (PubMed).
: "Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions?" in: British journal of pharmacology, Vol. 171, Issue 11, pp. 2751-66, (2014) (PubMed).
: "Inhibition of vascular calcification by block of intermediate conductance calcium-activated potassium channels with TRAM-34." in: Pharmacological research, Vol. 85, pp. 6-14, (2014) (PubMed).
: "PKA reduces the rat and human KCa3.1 current, CaM binding, and Ca2+ signaling, which requires Ser332/334 in the CaM-binding C terminus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 40, pp. 13371-83, (2014) (PubMed).
: "IK1 channel activity contributes to cisplatin sensitivity of human epidermoid cancer cells." in: American journal of physiology. Cell physiology, Vol. 294, Issue 6, pp. C1398-406, (2008) (PubMed).
: "Role of the NH2 terminus in the assembly and trafficking of the intermediate conductance Ca2+-activated K+ channel hIK1." in: The Journal of biological chemistry, Vol. 279, Issue 15, pp. 15531-40, (2004) (PubMed).
: "The hSK4 (KCNN4) isoform is the Ca2+-activated K+ channel (Gardos channel) in human red blood cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 12, pp. 7366-71, (2003) (PubMed).
Synonyms and alternative names related to KCNN4
potassium calcium-activated channel subfamily N member 4 (KCNN4), potassium calcium-activated channel subfamily N member 4 (Kcnn4), potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (Kcnn4), hIKCa1, hKCa4, hSK4, IK1, IKCA1, KCa3.1, KCA4, mIKCa1, rKCNN4c, rSK4, SK4, SKCasProtein level used designations for KCNN4
- intermediate conductance calcium-activated potassium channel protein 4
- intermediate-conductance calcium-activated potassium channel
- intermediate conductance calcium-activated potassium channel protein 1
- potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
- intermediate conductance calcium-activated potassium channel protein 4-like
- SKCa 4
- SKCa4
- putative Gardos channel
- putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel
- IK1
- KCa4
- SK4
- intermediate conductance K channel
- intermediate-conductance Ca-activated K channel
- potassium intermediate-small conductance calcium-activated channel subfamily N member 4
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