KCNU1 产品
(Potassium Channel, Subfamily U, Member 1 (KCNU1))
Categories
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+) (By similarity).
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Featured KCNU1 Categories
Recommended KCNU1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (1)
Cat. No.
ABIN7245455
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7269471
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6293996
Quantity
50 μL
Datasheet
Datasheet
Recommended KCNU1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3109066
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3131830
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3093421
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNU1 Products
: "SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 8, pp. 2599-604, (2015) (PubMed).: "Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 14, pp. 5879-84, (2011) (PubMed).
: "LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 48, pp. 19419-24, (2011) (PubMed).
: "The SLO3 sperm-specific potassium channel plays a vital role in male fertility." in: FEBS letters, Vol. 584, Issue 5, pp. 1041-6, (2010) (PubMed).
: "Mouse sperm K+ currents stimulated by pH and cAMP possibly coded by Slo3 channels." in: Biochemical and biophysical research communications, Vol. 381, Issue 2, pp. 204-9, (2009) (PubMed).
: "A novel, single, transmembrane protein CATSPERG is associated with CATSPER1 channel protein." in: Biology of reproduction, Vol. 81, Issue 3, pp. 539-44, (2009) (PubMed).
: "Interactions between beta subunits of the KCNMB family and Slo3: beta4 selectively modulates Slo3 expression and function." in: PLoS ONE, Vol. 4, Issue 7, pp. e6135, (2009) (PubMed).
Synonyms and alternative names related to KCNU1
potassium channel, subfamily U, member 1 (Kcnu1), potassium calcium-activated channel subfamily U member 1 (KCNU1), KCa5, KCa5.1, Kcnma3, KCNMC1, mSlo3, Slo3Protein level used designations for KCNU1
- KSper
- calcium-activated potassium channel subunit alpha-3
- calcium-activated potassium channel, subfamily M subunit alpha-3
- pH-sensitive maxi potassium channel
- pore-forming subunit of the sperm-specific alkalization activated K(+) current
- potassium channel subfamily U member 1
- potassium large conductance pH-sensitive channel, subfamily M, alpha member 3
- slowpoke homolog 3
- Calcium-activated potassium channel subunit alpha-3
- Calcium-activated potassium channel, subfamily M subunit alpha-3
- Slowpoke homolog 3
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