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ITCH 抗体

(Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
ITCH 抗体 ITCH 抗体 ITCH 抗体 (ABIN7258510)

ITCH 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

ITCH 抗体  (Internal Region) ITCH 抗体  (Internal Region) ITCH 抗体 (Internal Region) (ABIN334426)

Verified ITCH 适用: 人 ELISA, FACS, IF, WB 宿主: 山羊 Polyclonal unconjugated

ITCH 抗体 ITCH 抗体 ITCH 抗体 (ABIN7268032)

KO Validated ITCH 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

ITCH 抗体 by Grade

Find ITCH 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ITCH 抗体 by 适用

Find ITCH 抗体 for a variety of species such as anti-Human ITCH, anti-Mouse ITCH, anti-Rat ITCH. The species listed below are among those available. Click on a link to go to the corresponding products.

ITCH 抗体 by 应用范围

Find ITCH 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

ITCH 抗体 by 抗体来源

Find ITCH 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

ITCH 抗体 by 抗原表位

Find ITCH 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

ITCH 抗体 by 克隆形成能力

Find available monoclonal or polyclonal ITCH 抗体. Click on a link to go to the corresponding products.

ITCH 抗体 by 克隆

Find ITCH 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

ITCH 抗体 by 标记

Find ITCH 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ITCH 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN7180034
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, WB
Validations
  • (2)
Cat. No. ABIN7151041
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN7268033
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN3043253
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, ELISA
Validations
  • (2)
Cat. No. ABIN529491
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7127583
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7139004
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN1532110
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN1533142
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN6262676
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2774796
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Horse, Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN6743170
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC (p)
Validations
Cat. No. ABIN6283531
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
Cat. No. ABIN6283491
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7151042
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ITCH 抗体

Bozóky, Savchenko, Csermely, Korcsmáros, Dúl, Pontén, Székely, Klein: "Novel signatures of cancer-associated fibroblasts." in: International journal of cancer, Vol. 133, Issue 2, pp. 286-93, (2013) (PubMed).

Di Marcotullio, Ferretti, Greco, De Smaele, Po, Sico, Alimandi, Giannini, Maroder, Screpanti, Gulino: "Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination." in: Nature cell biology, Vol. 8, Issue 12, pp. 1415-23, (2006) (PubMed).

Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

Courbard, Fiore, Adélaïde, Borg, Birnbaum, Ollendorff: "Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45267-75, (2002) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Perry, Hustad, Swing, OSullivan, Jenkins, Copeland: "The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice." in: Nature genetics, Vol. 18, Issue 2, pp. 143-6, (1998) (PubMed).

Aliases for ITCH 抗体

itchy E3 ubiquitin protein ligase (ITCH) 抗体
itchy, E3 ubiquitin protein ligase (Itch) 抗体
itchy E3 ubiquitin protein ligase (Itch) 抗体
6720481N21Rik 抗体
8030492O04Rik 抗体
A130065M08 抗体
AIF4 抗体
AIP4 抗体
C230047C07Rik 抗体
dJ468O1.1 抗体
NAPP1 抗体
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