ITCH 抗体
(Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| ITCH 抗体 (AA 509-536) (Biotin) | 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (AA 509-536) (PE) | 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (AA 509-536) | 人, 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (AA 92-191) | 人 | 小鼠 Monoclonal |
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| ITCH 抗体 (AA 509-536) | 人, 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (N-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ITCH 抗体 (AA 29-303) (HRP) | 人 | 兔 Polyclonal |
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| ITCH 抗体 (AA 29-303) (FITC) | 人 | 兔 Polyclonal |
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| ITCH 抗体 (AA 29-303) (Biotin) | 人 | 兔 Polyclonal |
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| ITCH 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| ITCH 抗体 (pTyr420) | 人, 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (Tyr774) | 人, 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 | 人 | 小鼠 Polyclonal |
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| ITCH 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| ITCH 抗体 | 人, 小鼠, 大鼠 | 兔 Monoclonal |
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| ITCH 抗体 (AA 386-435) | 人, 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (pTyr420) | 人, 小鼠 | 兔 Polyclonal |
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| ITCH 抗体 (N-Term) | 人, 大鼠, Cow, 兔, 犬, 马, 豚鼠 | 兔 Polyclonal |
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| ITCH 抗体 (AA 17-358) (APC) | 人, 小鼠, 大鼠 | 小鼠 Monoclonal |
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| ITCH 抗体 (Middle Region) (APC) | 人, 小鼠, 大鼠, 猴 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 509-536
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- PE
- 抗体亚型
- IgG
- 抗原表位
- AA 509-536
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 509-536
Primary Antibody
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 标记
- unconjugated
- 抗体亚型
- IgG2b kappa
- 抗原表位
- AA 92-191
Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 509-536
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 40-90, N-Term
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- HRP
- 抗体亚型
- IgG
- 抗原表位
- AA 29-303
Primary Antibody
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- FITC
- 抗体亚型
- IgG
- 抗原表位
- AA 29-303
Primary Antibody
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 29-303
Primary Antibody
- ELISA (ELISA: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- pTyr420
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Tyr774
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 386-435
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 386-435, pTyr420
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 大鼠, Cow, 兔, 犬, 马, 豚鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 5E12
- 标记
- APC
- 抗体亚型
- IgG2b
- 抗原表位
- AA 17-358
Primary Antibody
- WB (Western Blotting: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠, 猴
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- APC
- 抗体亚型
- IgG
- 抗原表位
- Middle Region
Latest Publications for our ITCH 抗体
: "Novel signatures of cancer-associated fibroblasts." in: International journal of cancer, Vol. 133, Issue 2, pp. 286-93, (2013) (PubMed).
: "Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination." in: Nature cell biology, Vol. 8, Issue 12, pp. 1415-23, (2006) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
: "Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45267-75, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice." in: Nature genetics, Vol. 18, Issue 2, pp. 143-6, (1998) (PubMed).
: "Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination." in: Nature cell biology, Vol. 8, Issue 12, pp. 1415-23, (2006) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
: "Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45267-75, (2002) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice." in: Nature genetics, Vol. 18, Issue 2, pp. 143-6, (1998) (PubMed).
Aliases for ITCH 抗体
itchy E3 ubiquitin protein ligase (ITCH) 抗体itchy, E3 ubiquitin protein ligase (Itch) 抗体
itchy E3 ubiquitin protein ligase (Itch) 抗体
6720481N21Rik 抗体
8030492O04Rik 抗体
A130065M08 抗体
AIF4 抗体
AIP4 抗体
C230047C07Rik 抗体
dJ468O1.1 抗体
NAPP1 抗体
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