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ITCH 抗体

KO Validated ITCH 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7268032
发货至: 中国
  • 抗原 See all ITCH 抗体
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    适用
    • 37
    • 34
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 3
    • 1
    克隆类型
    • 46
    • 3
    单克隆
    标记
    • 27
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITCH antibody is un-conjugated
    应用范围
    • 34
    • 33
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    原理
    [KO Validated] ITCH Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    质量等级
    KO Validated
    免疫原
    A synthesized peptide derived from human ITCH
    亚型
    IgG
    Top Product
    Discover our top product ITCH Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    别名
    ITCH (ITCH 产品)
    别名
    AIF4 antibody, AIP4 antibody, NAPP1 antibody, dJ468O1.1 antibody, 6720481N21Rik antibody, 8030492O04Rik antibody, A130065M08 antibody, C230047C07Rik antibody, itchy E3 ubiquitin protein ligase antibody, itchy, E3 ubiquitin protein ligase antibody, ITCH antibody, Itch antibody
    背景
    This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],ADMFD, AIF4, AIP4, NAPP1,Apoptosis,Cell Biology & Developmental Biology,Immunology & Inflammation,NF-kB Signaling Pathway,Notch Signaling Pathway,Signal Transduction,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,ITCH
    分子量
    103kDa
    基因ID
    83737
    UniProt
    Q96J02
    途径
    Activation of Innate immune Response, CXCR4-mediated Signaling Events
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