IL-7 蛋白
(Interleukin 7 (IL7))
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010].
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45 results
IL7
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
IL7
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
Active
1 image
IL7
宿主: 小鼠
宿主: 人细胞
Recombinant
> 95 % as determined by SDS-PAGE
Active
1 image
IL7
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL7
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 95 % as determined by reducing SDS-PAGE.
IL7
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
IL7
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 90% by SDS-PAGE
SDS
Latest Publications for our IL-7 蛋白
: "gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis." in: Blood, Vol. 115, Issue 12, pp. 2380-90, (2010) (PubMed).: "Ikaros regulates Notch target gene expression in developing thymocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6265-74, (2008) (PubMed).
: "Interleukin-7: a new hematopoietic growth factor." in: Progress in clinical and biological research, Vol. 338, pp. 65-73, (1990) (PubMed).
: "Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 302-6, (1989) (PubMed).
: "Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 16, pp. 5894-8, (1986) (PubMed).
Aliases for IL-7 蛋白
interleukin 7 (IL7) 蛋白interleukin 7 (Il7) 蛋白
A630026I06Rik 蛋白
hlb368 蛋白
IL-7 蛋白
Il-7 蛋白
IL7 蛋白
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