IKBKG 产品
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
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This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011].
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Featured IKBKG Categories
IKBKG 抗体
High quality antibodies with extensive validation data.
IKBKG ELISA试剂盒
Reliable ELISA kits for a wide range of species.
IKBKG 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended IKBKG 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (7)
Cat. No.
ABIN3021151
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), PLA
Validations
- (6)
Cat. No.
ABIN563664
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN7189515
Quantity
100 μg
Datasheet
Datasheet
Recommended IKBKG ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6967600
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956745
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1145037
Quantity
96 tests
Datasheet
Datasheet
Recommended IKBKG 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7562620
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7554704
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123431
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our IKBKG Products
: "Placental Expression of NEMO Protein in Normal Pregnancy and Preeclampsia." in: Disease markers, Vol. 2019, pp. 8418379, (2019) (PubMed).: "Premature aging and cancer development in transgenic mice lacking functional CYLD." in: Aging, Vol. 11, Issue 1, pp. 127-159, (2019) (PubMed).
: "Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO." in: Virology, Vol. 502, pp. 33-38, (2017) (PubMed).
: "Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 36, pp. 10127-32, (2016) (PubMed).
: "iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus." in: Journal of proteomics, Vol. 130, pp. 65-75, (2016) (PubMed).
: "HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains." in: Oncogene, Vol. 34, Issue 3, pp. 334-45, (2015) (PubMed).
: "Identification of new IκBα complexes by an iterative experimental and mathematical modeling approach." in: PLoS computational biology, Vol. 10, Issue 3, pp. e1003528, (2014) (PubMed).
: "Hepatitis A virus 3C protease cleaves NEMO to impair induction of beta interferon." in: Journal of virology, Vol. 88, Issue 17, pp. 10252-8, (2014) (PubMed).
: "The LCR at the IKBKG locus is prone to recombine." in: American journal of human genetics, Vol. 86, Issue 4, pp. 650-2; author reply 652-3, (2010) (PubMed).
: "NEMO gene mutations in Chinese patients with incontinentia pigmenti." in: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 109, Issue 3, pp. 192-200, (2010) (PubMed).
Synonyms and alternative names related to IKBKG
inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), inhibitor of kappaB kinase gamma (Ikbkg), inhibitor of nuclear factor kappa B kinase subunit gamma (Ikbkg), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (ikbkg), inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog (ikbkg.L), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG_1), inhibitor of nuclear factor kappa B kinase subunit gamma (ikbkg), kenny (key), 1110037D23Rik, AI848108, AI851264, AMCBX1, AW124339, CG16910, dIKK, dIKK-gamma, Dmel\\CG16910, DmIKK-gamma, DmIKKgamma, Dmikkgamma, dmIKKgamma, FIP-3, FIP3, Fip3p, fj33c07, IKBKG, IKBKG_1, IKBKG_2, IKK, IKK-gamma, IKKg, IKKgamma, IKK[g], IKK[[gamma]], IP, IP1, IP2, IPD2, Kenny, KEY, Key, MGC97885, NEMO, Nemo, nemo, wu:fj33c07, ZC2HC9, zgc:113492Protein level used designations for IKBKG
- I-kappa-B kinase subunit gamma
- IKKAP1
- IKKG
- IkB kinase gamma subunit
- NF-kappa-B essential modifier
- NF-kappa-B essential modulator
- NFkappaB essential modulator
- ikB kinase subunit gamma
- ikB kinase-associated protein 1
- incontinentia pigmenti
- inhibitor of nuclear factor kappa-B kinase subunit gamma
- IKK-gamma
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- mFIP-3
- I-kappa-B kinase gamma
- NEMO
- NF-kappa B essential modulator
- inhibitor of kappaB kinase gamma
- ikky
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 1
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform 2
- NF-kappa-B essential modulator-like
- CG16910-PA
- CG16910-PB
- key-PA
- key-PB
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