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IkappaB-epsilon 产品

(IkappaB-epsilon)

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The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011].

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Recommended IkappaB-epsilon ELISA试剂盒

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Latest Publications for our IkappaB-epsilon Products

Page, Fischer, Baumgartner, Haas, Kreusel, Loidl, Hayn, Ziegler-Heitbrock, Neumeier, Brand: "4-Hydroxynonenal prevents NF-kappaB activation and tumor necrosis factor expression by inhibiting IkappaB phosphorylation and subsequent proteolysis." in: The Journal of biological chemistry, Vol. 274, Issue 17, pp. 11611-8, (1999) (PubMed).

Fischer, Page, Weber, Eisele, Neumeier, Brand: "Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IkappaB kinase signalsome activation and IkappaB proteolysis." in: The Journal of biological chemistry, Vol. 274, Issue 35, pp. 24625-32, (1999) (PubMed).

Simeonidis, Liang, Chen, Thanos: "Cloning and functional characterization of mouse IkappaBepsilon." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 26, pp. 14372-7, (1998) (PubMed).

Whiteside, Epinat, Rice, Israël: "I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity." in: The EMBO journal, Vol. 16, Issue 6, pp. 1413-26, (1997) (PubMed).

Synonyms and alternative names related to IkappaB-epsilon

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon (Nfkbie), NFKB inhibitor epsilon (NFKBIE), IKBE

Protein level used designations for IkappaB-epsilon

  • I-kappa-B-epsilon
  • NF-kappa-B inhibitor epsilon
  • NF-kappa-BIE
  • ikB-E
  • ikB-epsilon
  • ikappaBepsilon
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
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