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HSD11B1 抗体

(Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].

Active filters:

  • 抗原: HSD11B1
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6916422
Recombinant HSD11B1 抗体 (Alexa Fluor 647) HSD11B1 · Primary Antibody 人, 大鼠, 小鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6833492
Recombinant HSD11B1 抗体 (Alexa Fluor 594) HSD11B1 · Primary Antibody 人, 大鼠, 小鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6873745
Recombinant HSD11B1 抗体 (Biotin) HSD11B1 · Primary Antibody 人, 大鼠, 小鼠 兔 Monoclonal
  • 100 μL
发货至: 中国
ABIN6330366
HSD11B1 抗体 HSD11B1 · Primary Antibody 大鼠 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 1 mL
  • 20 μL
  • 50 μL
  • 100 μL
  • 200 μL
发货至: 中国
ABIN6330364
HSD11B1 抗体 HSD11B1 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 1 mL
  • 20 μL
  • 50 μL
  • 100 μL
  • 200 μL
发货至: 中国
ABIN8122132
HSD11B1 抗体 (AA 20-50) HSD11B1 · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • 50 μL
发货至: 中国
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 647
蛋白类型
Recombinant Antibody
产品编号 ABIN6916422
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Alexa Fluor 594
蛋白类型
Recombinant Antibody
产品编号 ABIN6833492
Primary Antibody
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Monoclonal
标记
Biotin
蛋白类型
Recombinant Antibody
产品编号 ABIN6873745
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
大鼠
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN6330366
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
产品编号 ABIN6330364
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 20-50
产品编号 ABIN8122132

Latest Publications for our HSD11B1 抗体

Oleinik, Kim, Roth, Selvam, Gooz, Johnson, Lemasters, Ogretmen: "Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress." in: Science advances, Vol. 5, Issue 9, pp. eaax1978, (2019) (PubMed).

Liu, Guo, Wang, Zhu, Li, Mi, Myatt, Sun: "Inhibition of Lysyl Oxidase by Cortisol Regeneration in Human Amnion: Implications for Rupture of Fetal Membranes." in: Endocrinology, Vol. 157, Issue 10, pp. 4055-4065, (2017) (PubMed).

Matsumura, Terao, Itami, Katayama: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).

Nakata, Umeda, Masuzaki, Sawai: "The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats." in: BMC oral health, Vol. 16, Issue 1, pp. 108, (2016) (PubMed).

Xu, Zhao, Lin, Xiang, Wang, Ye, Huang: "Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator." in: Fertility and sterility, Vol. 102, Issue 1, pp. 282-290.e4, (2014) (PubMed).

Kuroda, Venkatakrishnan, Salker, Lucas, Shaheen, Kuroda, Blanks, Christian, Quenby, Brosens: "Induction of 11?-HSD 1 and activation of distinct mineralocorticoid receptor- and glucocorticoid receptor-dependent gene networks in decidualizing human endometrial stromal cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 192-202, (2013) (PubMed).

Lei, Chen, Georgiou, Sooranna, Khanjani, Brosens, Bennett, Johnson: "Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1?-induced COX-2 expression in human term myometrial cells." in: PLoS ONE, Vol. 7, Issue 11, pp. e50167, (2012) (PubMed).

Sinclair, Walker, Burdon, van Beek, Kema, Hughes, Murray, Nightingale, Stewart, Rauz, Tomlinson: "Cerebrospinal fluid corticosteroid levels and cortisol metabolism in patients with idiopathic intracranial hypertension: a link between 11beta-HSD1 and intracranial pressure regulation?" in: The Journal of clinical endocrinology and metabolism, Vol. 95, Issue 12, pp. 5348-56, (2010) (PubMed).

Paterson, Morton, Fievet, Kenyon, Holmes, Staels, Seckl, Mullins: "Metabolic syndrome without obesity: Hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 18, pp. 7088-93, (2004) (PubMed).

Aliases for HSD11B1 抗体

hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1) 抗体
hydroxysteroid (11-beta) dehydrogenase 1b (HSD11B1b) 抗体
hydroxysteroid (11-beta) dehydrogenase 1 L homeolog (hsd11b1.L) 抗体
hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1) 抗体
11-beta-HSD1 抗体
11-DH 抗体
CORTRD2 抗体
HDL 抗体
HSD11 抗体
hsd11 抗体
HSD11B 抗体
hsd11b 抗体
HSD11L 抗体
LRRGT00065 抗体
SDR26C1 抗体
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