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HSD11B1 抗体 (AA 20-50)

The 兔 多克隆 anti-HSD11B1 antibody (ABIN8122132) specifically detects HSD11B1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN8122132
发货至: 中国
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Quick Overview for HSD11B1 抗体 (AA 20-50) (ABIN8122132)

抗原

See all HSD11B1 抗体
HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

适用

  • 80
  • 46
  • 44
  • 12
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 76
  • 7
  • 2
兔

克隆类型

  • 64
  • 21
多克隆

标记

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  • 5
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  • 3
  • 3
  • 3
  • 3
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  • 3
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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This HSD11B1 antibody is un-conjugated

应用范围

  • 44
  • 30
  • 18
  • 16
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 18
    • 12
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-50

    原理

    11β-HSD1 Antibody

    特异性

    11β-HSD1 Polyclonal Antibody detects endogenous levels of 11β-HSD1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from 11beta-HSD1 . at AA range: 20-50

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))

    别名

    11beta-HSD1

    背景

    Synonyms: HSD11B1, HSD11, HSD11L, Corticosteroid 11-beta-dehydrogenase isozyme 1, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1

    Background: hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011],

    Gene Name: HSD11B1

    Protein Name: Corticosteroid 11-beta-dehydrogenase isozyme 1

    基因ID

    3290

    UniProt

    P28845

    途径

    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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