HRPT2 抗体
(Parafibromin (CDC73))
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009].
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44 results :
KD Validated
CDC73
适用: 人, 小鼠, 大鼠
WB
宿主: 兔
Monoclonal
unconjugated
Recombinant Antibody
CDC73
适用: 人
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our HRPT2 抗体
: "Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5675-80, (2012) (PubMed).: "The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression." in: Nucleic acids research, Vol. 38, Issue 2, pp. 382-90, (2010) (PubMed).
: "The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs." in: Nucleic acids research, Vol. 38, Issue 21, pp. 7637-50, (2010) (PubMed).
: "The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 3, pp. 755-60, (2009) (PubMed).
: "Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice." in: Molecular and cellular biology, Vol. 28, Issue 9, pp. 2930-40, (2008) (PubMed).
: "The parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 45, pp. 17420-5, (2008) (PubMed).
: "Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains." in: Genes & development, Vol. 22, Issue 4, pp. 528-42, (2008) (PubMed).
: "Parafibromin immunoreactivity: its use as an additional diagnostic marker for parathyroid tumor classification." in: Endocrine-related cancer, Vol. 14, Issue 2, pp. 501-12, (2007) (PubMed).
: "Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo." in: Cell, Vol. 125, Issue 2, pp. 327-41, (2006) (PubMed).
: "BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling." in: Mechanisms of development, Vol. 124, Issue 1, pp. 59-67, (2006) (PubMed).
Aliases for HRPT2 抗体
cell division cycle 73 (CDC73) 抗体cell division cycle 73, Paf1/RNA polymerase II complex component (Cdc73) 抗体
cell division cycle 73 (Cdc73) 抗体
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (cdc73) 抗体
cell division cycle 73 (cdc73) 抗体
parafibromin (Tsp_03925) 抗体
parafibromin (Tsp_04052) 抗体
parafibromin (Tsp_04125) 抗体
cell division cycle 73 S homeolog (cdc73.S) 抗体
8430414L16Rik 抗体
BC027756 抗体
C1orf28 抗体
C81219 抗体
C130030P16Rik 抗体
cdc73 抗体
HPTJT 抗体
HRPT2 抗体
Hrpt2 抗体
hrpt2 抗体
HYX 抗体
LOC100222932 抗体
MGC108428 抗体
zgc:63956 抗体
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