HRPT2 抗体 (AA 51-100)
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Quick Overview for HRPT2 抗体 (AA 51-100) (ABIN7230498)
抗原
See all HRPT2 (CDC73) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-100
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原理
- Rabbit Anti-Parafibromin Polyclonal Antibody
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特异性
- This antibody detects endogenous levels of Parafibromin
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human Parafibromin protein at AA range: 51-100
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- HRPT2 (CDC73) (Parafibromin (CDC73))
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别名
- Parafibromin
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背景
- Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 proteinCDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in CDC73 have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
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分子量
- 60kD
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基因ID
- 79577
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UniProt
- Q6P1J9
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途径
- Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
抗原
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