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HRas proto-oncogene, GTPase 抗体

(HRas proto-oncogene, GTPase (HRAS))
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008].

100 results :

HRAS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
Pubmed 4 references
产品编号 ABIN2857002
 
HRAS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C2 unconjugated
产品编号 ABIN1498713
 
HRAS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3029525
 
HRAS 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
产品编号 ABIN1498715
 
HRAS 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB15622 unconjugated
Pubmed 2 references
产品编号 ABIN392183
 
HRAS 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3031138
 
HRAS 适用: 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7178885
 
HRAS 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7154617
 
HRAS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal H-Ras-03 unconjugated
Pubmed 1 reference
产品编号 ABIN2473919
 
HRAS 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN516687
 
HRAS 适用: 人 WB 宿主: 小鼠 Monoclonal H-RAS-03 unconjugated
产品编号 ABIN302083
 
HRAS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6141983
 
HRAS 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7267785
 
HRAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1980538
 
HRAS 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB14565 unconjugated
产品编号 ABIN655622
 
HRAS 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN952792
 
HRAS 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IP, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN737226
 
HRAS 适用: 人, 大鼠 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1903338
 
HRAS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN516686
 
HRAS 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3028695
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunoprecipitation (IP)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunocytochemistry (ICC)
    • Enzyme Immunoassay (EIA)
    • Flow Cytometry (FACS)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Luminex Assay (LMNX)
    • Neutralization (Neut)
    • Proximity Ligation Assay (PLA)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Rat
    • Chicken
    • Monkey
    • Dog
    • Hamster
    • Pig
    • Cow
    • Drosophila melanogaster
    • Fish
    • Guinea Pig
    • Horse
    • Rabbit
    • Xenopus laevis
    • Zebrafish (Danio rerio)
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Rat
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • H-Ras-03
    • 1A1
    • 1C2
    • BEA-8
    • H-RAS-03
    • OTI1G8
    • PT0590R
    • R01-7D0
    • RB14565
    • RB15622
    • Y13-259
  • 抗原表位
    • AA 101-152
    • AA 51-150
    • AA 151-179
    • C-Term
    • AA 2-186
    • AA 12-181
    • AA 82-176
    • AA 1-189
    • Middle Region
    • AA 104-128
    • AA 111-189
    • AA 146-176
    • AA 153-184
    • AA 111-137
    • AA 111-176
    • AA 62-76
    • N-Term
  • 标记
    • 非结合性
    • FITC
    • Biotin
    • HRP
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • AbBy Fluor® 680
    • AbBy Fluor® 750
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • APC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • PE
  • 抗体亚型
    • IgG
    • Ig Fraction
    • IgG1
    • IgG2b
    • kappa
    • IgG1 kappa
    • IgG2a
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
  • Supplier
    • antibodies-online
    • FabGennix
    • Signalway
    • NSJ Bioreagents
    • Biomatik
    • Abbexa
    • Abcepta
    • Acris
    • Boster Bio
    • CUSABIO
    • Cloud-Clone
    • OriGene
    • RayBiotech
    • USBio
    • Wuhan Fine biotech

Latest Publications for our HRas proto-oncogene, GTPase 抗体

Basu, Lee, Salotti, Basu, Sakchaisri, Xiao, Walia, Westlake, Morrison, Johnson: "Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets." in: Cancer research, Vol. 78, Issue 4, pp. 891-908, (2019) (PubMed).

Brandt, Albers, Hejhal, Pfundstein, Gonçalves, Catalano, Wild, Frew: "Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma." in: Oncotarget, Vol. 9, Issue 28, pp. 19753-19766, (2018) (PubMed).

Gao, Wang, Jin, Hu, Duan, Shi, Du, Song, Yang, Li, Han, Zhao, Zhang, Fan, Miao: "Nogo-B receptor increases the resistance to tamoxifen in estrogen receptor-positive breast cancer cells." in: Breast cancer research : BCR, Vol. 20, Issue 1, pp. 112, (2018) (PubMed).

Brandt, Albers, Hejhal, Catalano, Wild, Frew: "Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma." in: PLoS ONE, Vol. 12, Issue 10, pp. e0186102, (2017) (PubMed).

Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

Maemoto, Yumoto, Ibata, Torizuka, Ozawa, Tatsumi, Hashido, Morikawa, Maeda, Imai: "Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines." in: Odontology / the Society of the Nippon Dental University, Vol. 100, Issue 2, pp. 149-55, (2012) (PubMed).

Ma, Liu, Wu, Terada: "p66(Shc) restrains Ras hyperactivation and suppresses metastatic behavior." in: Oncogene, Vol. 29, Issue 41, pp. 5559-67, (2010) (PubMed).

Pearl, Prodromou, Workman: "The Hsp90 molecular chaperone: an open and shut case for treatment." in: The Biochemical journal, Vol. 410, Issue 3, pp. 439-53, (2008) (PubMed).

Millson, Truman, Rácz, Hu, Panaretou, Nuttall, Mollapour, Söti, Piper et al.: "Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates ..." in: The FEBS journal, Vol. 274, Issue 17, pp. 4453-63, (2007) (PubMed).

Hooven, Yamamoto, Jeffery: "Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis." in: The International journal of developmental biology, Vol. 48, Issue 8-9, pp. 731-8, (2004) (PubMed).

Aliases for HRas proto-oncogene, GTPase 抗体

HRas proto-oncogene, GTPase (HRAS) 抗体
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a (hrasa) 抗体
neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene (LOC733587) 抗体
HRas proto-oncogene, GTPase (Hras) 抗体
Harvey rat sarcoma viral oncogene homolog L homeolog (hras.L) 抗体
Harvey rat sarcoma viral oncogene homolog (hras) 抗体
Harvey rat sarcoma virus oncogene (Hras) 抗体
NRAS proto-oncogene, GTPase (NRAS) 抗体
resistance to audiogenic seizures (ras) 抗体
-Ha-ras Harvey rat sarcoma viral oncogene homolog b (hrasb) 抗体
asr 抗体
C-BAS/HAS 抗体
c-bas/has 抗体
C-H-RAS 抗体
c-H-ras 抗体
c-Ha-ras 抗体
C-HA-RAS1 抗体
c-rasHa 抗体
CTLO 抗体
H-RAS 抗体
H-Ras 抗体
H-ras 抗体
H-RASIDX 抗体
Ha-ras 抗体
HAMSV 抗体
Harvey-ras 抗体
hras 抗体
HRAS 抗体
Hras-1 抗体
HRAS1 抗体
hras1 抗体
hrasl 抗体
K-RAS 抗体
K-Ras 抗体
Kras2 抗体
N-RAS 抗体
N-Ras 抗体
ras 抗体
RASH1 抗体
rash1 抗体
zgc:110250 抗体
zgc:110734 抗体
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