HERC5 抗体
(Hect Domain and RLD 5 (HERC5))
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq, Jul 2008].
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15 results
HERC5
适用: 人, Cow, 马, 兔, 猴
WB, IHC, IHC (p)
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our HERC5 抗体
: "Covalent ISG15 conjugation positively regulates the ubiquitin E3 ligase activity of parkin." in: Open biology, Vol. 6, Issue 8, (2016) (PubMed).: "90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus." in: Neoplasia (New York, N.Y.), Vol. 18, Issue 10, pp. 618-625, (2016) (PubMed).
: "Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export." in: Retrovirology, Vol. 11, pp. 27, (2014) (PubMed).
: "Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag." in: Retrovirology, Vol. 8, pp. 95, (2011) (PubMed).
Aliases for HERC5 抗体
HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5) 抗体hect domain and RLD 5 (HERC5) 抗体
CEB1 抗体
CEBP1 抗体
HERC5 抗体
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