HBEGF 蛋白
(Heparin-Binding EGF-Like Growth Factor (HBEGF))
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
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22 results
HBEGF
宿主: 人
宿主: 人细胞
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
Aliases for HBEGF 蛋白
heparin-binding EGF-like growth factor b (hbegfb) 蛋白heparin binding EGF like growth factor (HBEGF) 蛋白
Heparin-binding EGF-like growth factor (hbegf) 蛋白
heparin-binding EGF-like growth factor a (hbegfa) 蛋白
heparin-binding EGF-like growth factor (Hbegf) 蛋白
AW047313 蛋白
DTR 蛋白
Dtr 蛋白
DTS 蛋白
Dts 蛋白
DTSF 蛋白
GFHB 蛋白
Hb-egf 蛋白
HB-EGF 蛋白
hbegf 蛋白
HBEGF 蛋白
HEGFL 蛋白
Hegfl 蛋白
zgc:165443 蛋白
zgc:175091 蛋白
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