GRP78 蛋白
(Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| GRP78 Protein (AA 19-654, full length) (His tag) | 人 | Mammalian Cells |
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| GRP78 Protein (AA 19-654, full length) (His tag) | 人 | 酵母菌 |
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| GRP78 Protein (full length) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 19-654) (GST tag) | 人 | 小麦胚 |
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| GRP78 Protein (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 20-650) (His tag) | 人 | Baculovirus infected Insect Cells |
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| GRP78 Protein (AA 20-655) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 19-654) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 20-650) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 蛋白 | 人 | Hi-5 Cells |
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| GRP78 Protein (AA 20-655, full length) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 261-470) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 20-655) (GST tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 261-470) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 260-469) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 19-654) (GST tag) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 20-655) (His tag,GST tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (AA 20-655) (His tag) | 小鼠 | HEK-293F Cells |
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| GRP78 Protein (AA 25-293, partial) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| GRP78 Protein (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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Protein
- SDS (SDS-PAGE: 有验证图片)
- AcA (Activity Assay: 有验证图片)
- 宿主
- 人
- 宿主
- Mammalian Cells
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- AcA (Activity Assay: 有验证图片)
- 宿主
- 人
- 宿主
- 酵母菌
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- AcA (Activity Assay: 所列应用)
- Func (Functional Studies: 所列应用)
4 references - 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >90%
Protein
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
- 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- AcA (Activity Assay: 所列应用)
- Func (Functional Studies: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- >90%
- 生物活性
- Active
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 85 % as determined by SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- HEK-293F Cells
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- SDS (SDS-PAGE: 有验证图片)
- WB (Western Blotting: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Latest Publications for our GRP78 蛋白
: "Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction." in: Cell death and differentiation, Vol. 21, Issue 5, pp. 797-810, (2014) (PubMed).
: "Generation of human ER chaperone BiP in yeast Saccharomyces cerevisiae." in: Microbial cell factories, Vol. 13, pp. 22, (2014) (PubMed).
: "HKH40A downregulates GRP78/BiP expression in cancer cells." in: Cell death & disease, Vol. 5, pp. e1240, (2014) (PubMed).
: "Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis." in: BMC cancer, Vol. 13, pp. 96, (2013) (PubMed).
: "IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 4, pp. 1614-24, (2013) (PubMed).
: "A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death." in: PLoS ONE, Vol. 7, Issue 10, pp. e45690, (2012) (PubMed).
: "Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer." in: Gynecologic oncology, Vol. 115, Issue 1, pp. 112-20, (2009) (PubMed).
: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).
: "Human gene encoding the 78,000-dalton glucose-regulated protein and its pseudogene: structure, conservation, and regulation." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 4, pp. 275-86, (1988) (PubMed).
: "Generation of human ER chaperone BiP in yeast Saccharomyces cerevisiae." in: Microbial cell factories, Vol. 13, pp. 22, (2014) (PubMed).
: "HKH40A downregulates GRP78/BiP expression in cancer cells." in: Cell death & disease, Vol. 5, pp. e1240, (2014) (PubMed).
: "Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis." in: BMC cancer, Vol. 13, pp. 96, (2013) (PubMed).
: "IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 4, pp. 1614-24, (2013) (PubMed).
: "A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death." in: PLoS ONE, Vol. 7, Issue 10, pp. e45690, (2012) (PubMed).
: "Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer." in: Gynecologic oncology, Vol. 115, Issue 1, pp. 112-20, (2009) (PubMed).
: "Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry." in: Journal of proteome research, Vol. 8, Issue 3, pp. 1540-54, (2009) (PubMed).
: "Human gene encoding the 78,000-dalton glucose-regulated protein and its pseudogene: structure, conservation, and regulation." in: DNA (Mary Ann Liebert, Inc.), Vol. 7, Issue 4, pp. 275-86, (1988) (PubMed).
Aliases for GRP78 蛋白
78 kDa glucose-regulated protein (CpipJ_CPIJ003550) 蛋白heat shock protein family A (Hsp70) member 5 (HSPA5) 蛋白
78 kDa glucose-regulated protein (grp78) 蛋白
BiP/GRP78 (LOC100533358) 蛋白
glucose-regulated protein 78 (BiP/grp78) 蛋白
glucose-regulated protein 78 (Tc00.1047053506585.40) 蛋白
glucose-regulated protein 78 (Tb11.02.5450) 蛋白
glucose-regulated protein 78 (Tb11.02.5500) 蛋白
putative glucose-regulated protein 78 (LMJF_28_1200) 蛋白
Hsp70 family ATPase KAR2 (KAR2) 蛋白
78 kDa glucose-regulated protein (LOC100135840) 蛋白
heat shock protein family A (Hsp70) member 5 S homeolog (hspa5.S) 蛋白
heat shock 70 kDa protein 5a (hspa5) 蛋白
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5) 蛋白
heat shock protein family A (Hsp70) member 5 (Hspa5) 蛋白
heat shock protein 5 (Hspa5) 蛋白
heat shock protein family A member 5 (Hspa5) 蛋白
heat shock protein 5 (hspa5) 蛋白
AL022860 蛋白
AU019543 蛋白
baffled 蛋白
BiP 蛋白
BIP 蛋白
Bip 蛋白
cb865 蛋白
D2Wsu17e 蛋白
D2Wsu141e 蛋白
fb60h09 蛋白
fi36d04 蛋白
GRP-78 蛋白
GRP78 蛋白
grp78 蛋白
Grp78 蛋白
Hsce70 蛋白
hspa5a 蛋白
mBiP 蛋白
MIF2 蛋白
SEZ-7 蛋白
Sez7 蛋白
wu:fb60h09 蛋白
wu:fi36d04 蛋白
zgc:55994 蛋白
zgc:77606 蛋白
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