GSAP 蛋白
(Pigeon Homolog (PION))
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1\; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP\; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010].
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11 results
custom-made
PION
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
PION
宿主: 小鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
PION
宿主: 大鼠
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
SDS, WB, Imm, PC
PION
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 97 %
SDS, WB, Imm, PC
custom-made
PION
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Aliases for GSAP 蛋白
gamma-secretase activating protein (GSAP) 蛋白gamma-secretase activating protein (Gsap) 蛋白
A530088I07Rik 蛋白
PION 蛋白
Pion 蛋白
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- GS28 蛋白
- GRWD1 蛋白
- GRSF1 蛋白
- GRPR 蛋白
- GRPEL2 蛋白
- GRPEL1 蛋白
- GRP94 蛋白
- GRP78 蛋白
- GRP 蛋白
- Growth Hormone Regulated TBC Protein 1 蛋白
- Growth Hormone Receptor 蛋白
- Growth Hormone 2 蛋白
- Growth Hormone 1 蛋白
- Growth Arrest and DNA-Damage-Inducible, beta 蛋白
- GRO gamma 蛋白
- GRO beta Protein 蛋白
- GRO alpha Protein 蛋白
- GRM8 蛋白
- GRM7 蛋白
- GRM2 蛋白
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