GRB10 抗体
(Growth Factor Receptor-Bound Protein 10 (GRB10))
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010].
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50 results
GRB10
适用: 人, 小鼠
ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
Latest Publications for our GRB10 抗体
: "Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10475-84, (1998) (PubMed).: "Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains." in: The Journal of biological chemistry, Vol. 272, Issue 5, pp. 2659-67, (1997) (PubMed).
: "Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma." in: The Journal of biological chemistry, Vol. 272, Issue 46, pp. 29104-12, (1997) (PubMed).
: "Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling." in: The Journal of biological chemistry, Vol. 271, Issue 37, pp. 22506-13, (1996) (PubMed).
: "Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 22, pp. 10287-91, (1995) (PubMed).
Aliases for GRB10 抗体
growth factor receptor bound protein 10 (GRB10) 抗体growth factor receptor-bound protein 10a (grb10a) 抗体
growth factor receptor bound protein 10 (grb10) 抗体
growth factor receptor bound protein 10 L homeolog (grb10.L) 抗体
growth factor receptor-bound protein 10 (LOC100434903) 抗体
growth factor receptor bound protein 10 (Grb10) 抗体
5730571D09Rik 抗体
AI325020 抗体
grb-10 抗体
Grb-10 抗体
grb-ir 抗体
GRB-IR 抗体
grb10 抗体
GRB10 抗体
irbp 抗体
IRBP 抗体
LOC100224775 抗体
meg1 抗体
Meg1 抗体
MEG1 抗体
mKIAA0207 抗体
RGD1566234 抗体
rss 抗体
RSS 抗体
zgc:91987 抗体
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