GFI1 抗体
(Growth Factor Independent 1 (GFI1))
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| GFI1 抗体 (Alexa Fluor 555) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (Alexa Fluor 680) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (Alexa Fluor 647) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (Alexa Fluor 750) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (Alexa Fluor 594) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (Alexa Fluor 488) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (AA 1-422) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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| GFI1 抗体 (Biotin) | 人, 大鼠, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 大鼠, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-422
Latest Publications for our GFI1 抗体
: "Transcription factor induced conversion of human fibroblasts towards the hair cell lineage." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200210, (2019) (PubMed).
: "GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1." in: Nature communications, Vol. 9, Issue 1, pp. 1418, (2018) (PubMed).
: "Single-cell analysis of mixed-lineage states leading to a binary cell fate choice." in: Nature, Vol. 537, Issue 7622, pp. 698-702, (2017) (PubMed).
: "Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1." in: PLoS ONE, Vol. 11, Issue 7, pp. e0160344, (2017) (PubMed).
: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).
: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).
: "GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1." in: Nature communications, Vol. 9, Issue 1, pp. 1418, (2018) (PubMed).
: "Single-cell analysis of mixed-lineage states leading to a binary cell fate choice." in: Nature, Vol. 537, Issue 7622, pp. 698-702, (2017) (PubMed).
: "Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1." in: PLoS ONE, Vol. 11, Issue 7, pp. e0160344, (2017) (PubMed).
: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).
: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).
Aliases for GFI1 抗体
growth factor independent 1 (Gfi1) 抗体growth factor independent 1 transcriptional repressor (GFI1) 抗体
growth factor independent 1 transcriptional repressor (Gfi1) 抗体
AW495828 抗体
Gfi-1 抗体
GFI-1 抗体
GFI1 抗体
GFI1A 抗体
Pal-1 抗体
Pal1 抗体
SCN2 抗体
ZNF163 抗体
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