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GFI1 抗体 (AA 1-422)

The 兔 多克隆 anti-GFI1 antibody is suitable to detect GFI1 in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA, IHC (p) 和 FACS.
产品编号 ABIN7869342
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GFI1 抗体 (AA 1-422) (ABIN7869342)

抗原

See all GFI1 抗体
GFI1 (Growth Factor Independent 1 (GFI1))

适用

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  • 17
  • 16
  • 5
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  • 3
  • 3
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  • 1
  • 1
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人, 大鼠, 小鼠

宿主

  • 18
  • 7

克隆类型

  • 20
  • 5
多克隆

标记

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This GFI1 antibody is un-conjugated

应用范围

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  • 9
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • 抗原表位

    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-422

    原理

    GFI1 Antibody

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids M1-K422) was used as the immunogen for the GFI1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the GFI1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the GFI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    GFI1 (Growth Factor Independent 1 (GFI1))

    别名

    GFI1

    背景

    Zinc finger protein Gfi-1 is a transcriptional repressor that in humans is encoded by the GFI1 gene. It is mapped to 1p22.1. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

    UniProt

    Q99684
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