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- 抗原 See all GFI1 抗体
- GFI1 (Growth Factor Independent 1 (GFI1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GFI1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- GFI1 (growth factor independent 1 transcription repressor) is a transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5'-TAAATCAC[AT]GCA-3' in the promoter region of a large number of genes. Component of several complexes, including the EHMT2-GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required for granulocyte development. Mediates, together with U2AF1L4, the alternative splicing of CD45 and controls T-cell receptor signaling. Regulates the endotoxin-mediated Toll-like receptor (TLR) inflammatory response by antagonizing RELA. Cooperates with CBFA2T2 to regulate ITGB1-dependent neurite growth. Controls cell-cycle progression by repressing CDKNIA/p21 transcription in response to TGFB1 via recruitment of GFI1 by ZBTB17 to the CDKNIA/p21 and CDKNIB promoters. Required for the maintenance of inner ear hair cells. GFI1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- This antibody was raised against a peptide within the N-terminal region of human GFI1.
- 亚型
- IgG
- Top Product
- Discover our top product GFI1 Primary Antibody
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anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibody
GFI1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5D7 unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibodyGFI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-422) antibodyGFI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 32-81) antibodyGFI1 适用: 人, 大鼠, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 280-330) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- GFI1 (Growth Factor Independent 1 (GFI1))
- 别名
- GFI1 (GFI1 产品)
- 别名
- AW495828 antibody, Gfi-1 antibody, Pal-1 antibody, Pal1 antibody, GFI1 antibody, GFI-1 antibody, GFI1A antibody, SCN2 antibody, ZNF163 antibody, growth factor independent 1 antibody, growth factor independent 1 transcriptional repressor antibody, Gfi1 antibody, GFI1 antibody
- 分子量
- 55 kDa
- NCBI登录号
- NP_005254
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