GCN2 产品
(Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))
Categories
EIF2AK4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2S1\; MIM 603907) to downregulate protein synthesis in response to varied cellular stresses (Berlanga et al., 1999 [PubMed 10504407]).[supplied by OMIM, Mar 2008].
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Featured GCN2 Categories
Recommended GCN2 抗体
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Reactivity
Application
Validations
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Datasheet
Reactivity
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Application
WB, IHC, IF
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- (6)
Cat. No.
ABIN6140031
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN684943
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
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Validations
- (4)
Cat. No.
ABIN684958
Quantity
100 μL
Datasheet
Datasheet
Recommended GCN2 蛋白
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Cat. No.
ABIN5569537
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5 μg
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Datasheet
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Wheat germ
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Cat. No.
ABIN1352506
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ABIN1352508
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Latest Publications for our GCN2 Products
: "Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma." in: Scientific reports, Vol. 5, pp. 11781, (2015) (PubMed).: "Tryptophan depletion and the kinase GCN2 mediate IFN-?-induced autophagy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 6, pp. 2954-64, (2012) (PubMed).
: "The role of nitric-oxide synthase in the regulation of UVB light-induced phosphorylation of the alpha subunit of eukaryotic initiation factor 2." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24281-8, (2009) (PubMed).
: "The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress." in: Molecular and cellular biology, Vol. 27, Issue 15, pp. 5499-513, (2007) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
Synonyms and alternative names related to GCN2
eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4), eukaryotic translation initiation factor 2-alpha kinase 4 (LOC579979), eIF-2-alpha kinase GCN2 (LOC100187226), eukaryotic translation initiation factor 2 alpha kinase 4 (eif2ak4), eukaryotic translation initiation factor 2 alpha kinase 4 (Eif2ak4), 2610011M03, EIF2AK4, GCN2, Gcn2-like, MGCN2Protein level used designations for GCN2
- eukaryotic translation initiation factor 2 alpha kinase 4
- eukaryotic translation initiation factor 2-alpha kinase 4-like
- GCN2 protein
- GCN2 eIF2alpha kinase
- GCN2-like protein
- eukaryotic translation initiation factor 2-alpha kinase 4
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